Evidence map›Paper›PMID 40171535›Full record

ReviewFrontiers in neuroscience2025

Research progress in modulating the auditory system by the cochlear circadian clock system in response to noise exposure.

Xiaoqiong Song, Mengzhu Cheng, Cui Gu, Fenghan Wang, Kefeng Ma, Chunping Wang, Xiaojun She, Bo Cui

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoqiong Song *School of Public Health, Shandong Second Medical University, Weifang, Shandong, China.
Mengzhu Cheng *Academy of Military Medical Sciences, Tianjin, China.
Cui GuAcademy of Military Medical Sciences, Tianjin, China.
Fenghan WangAcademy of Military Medical Sciences, Tianjin, China.
Kefeng MaAcademy of Military Medical Sciences, Tianjin, China.
Chunping WangSchool of Public Health, Shandong Second Medical University, Weifang, Shandong, China.
Xiaojun SheAcademy of Military Medical Sciences, Tianjin, China.
Bo CuiSchool of Public Health, Shandong Second Medical University, Weifang, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circadian clock is an endogenous system evolved to adapt to environmental changes. Recent studies confirmed that the cochlea exhibits circadian oscillations regulating auditory function. These oscillations are linked to brain-derived neurotrophic factor and glucocorticoid levels. Circadian rhythms influence cochlear sensitivity to noise by regulating the secretion of brain-derived neurotrophic factors and glucocorticoids. This study explores the regulatory mechanism of the circadian clock system, its impact on the auditory system, and its potential role in noise-induced hearing loss. Understanding the regulatory mechanisms of circadian rhythms in auditory function will provide new ideas for developing treatments for noise-induced hearing loss.

Indexed as

circadian clockcircadian rhythmcochleanoisenoise-induced hearing loss

Identifiers

PMID40171535
PMCPMC11958988

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.