Evidence map›Paper›PMID 40171395›Full record

ArticleBJUI compass2025

Feasibility study of using the PREDICT kidney tool for patients with localised renal cell carcinoma.

Panayiotis Laouris, Chiara Re, Georgia Stimpson, Axel Bex, James Blackmur, Alexander Laird, Carley Batley, Grant D Stewart, Hannah Harrison, Juliet A Usher-Smith

Abstract read
In one paragraph

Article in BJUI compass, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Panayiotis LaourisDepartment of Public Health and Primary Care University of Cambridge Cambridge UK.
Chiara ReDepartment of Surgery University of Cambridge, Addenbrooke's Hospital Cambridge UK.ORCID https://orcid.org/0000-0001-8908-0817
Georgia StimpsonDepartment of Public Health and Primary Care University of Cambridge Cambridge UK.ORCID https://orcid.org/0000-0003-2795-9898
Axel BexRoyal Free London NHS Foundation Trust, UCL Division of Surgery and Interventional Science London UK.
James BlackmurWestern General Hospital, NHS Lothian Edinburgh UK.ORCID https://orcid.org/0000-0001-7267-837X
Alexander LairdWestern General Hospital, NHS Lothian Edinburgh UK.ORCID https://orcid.org/0000-0002-7296-025X
Carley BatleyDepartment of Oncology University of Cambridge, Addenbrooke's Hospital Cambridge UK.
Grant D StewartDepartment of Surgery University of Cambridge, Addenbrooke's Hospital Cambridge UK.ORCID https://orcid.org/0000-0003-3188-9140
Hannah HarrisonDepartment of Public Health and Primary Care University of Cambridge Cambridge UK.ORCID https://orcid.org/0000-0001-8952-852X
Juliet A Usher-SmithDepartment of Public Health and Primary Care University of Cambridge Cambridge UK.ORCID https://orcid.org/0000-0002-8501-2531

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Localised renal cell carcinoma (RCC) is usually treated surgically, with post-operative imaging-based surveillance to monitor for recurrence. However, surveillance practices vary widely, and patients often lack a clear understanding of their risk of recurrence and follow-up care. The PREDICT Kidney tool has been developed to enhance risk communication by providing individualised recurrence and mortality risk estimates. The tool uses the Leibovich score augmented with English national data to provide a personalised risk assessment of cancer recurrence and death from other causes, presented in both numerical and visual formats. Study Design: A multicentre, prospective feasibility study of incorporating the PREDICT Kidney risk communication tool into the first follow-up consultation for localised RCC patients post-surgery. Endpoints: Patient uptake into the study, completeness of data collection, consultation duration, the acceptability of the tool to both patients and clinicians, clinician adherence to the study "best-practice" guide, variability in tool usage across clinicians and sites and patient-level clinical outcomes including subjective and objective comprehension of risk of recurrence and follow-up, perceived risk of cancer recurrence, risk conviction, satisfaction with the information provided on risk of recurrence and follow-up, and fear of cancer recurrence. Patients and Methods: We aim to recruit 60 patients from three hospitals in England and Scotland. Patients treated with surgery for primary localised clear-cell RCC awaiting their first follow-up appointment will be invited to take part. Participants will be allocated into two groups: standard care and standard care supplemented with the use of the PREDICT Kidney tool. Data will be collected through questionnaires, audio/video recordings of consultations and interviews with a subset of patients and clinicians. The study period is planned from September 2024 to July 2025. The findings will guide the design of a future randomised controlled trial to evaluate the tool's efficacy in clinical settings.

Indexed as

feasibility trialkidney cancerrecurrence risksrisk communicationrisk estimates

Identifiers

PMID40171395
PMCPMC11955410

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.