Evidence map›Paper›PMID 40171393›Full record

ArticleBioscience of microbiota, food and health2025

Continuous intake of galacto-oligosaccharides containing syrup contributes to maintaining the health of household cats by modulating their gut microbiota.

Atsuko Hokkyo, Sayaka Kakiyama, Yuh Shiwa, Chiaki Kaga, Toshihide Kobayashi, Koji Nomoto, Naomi Harima-Mizusawa

Abstract read
In one paragraph

Article in Bioscience of microbiota, food and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Atsuko HokkyoYakult Honsha Co., Ltd., Central Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-0012, Japan.
Sayaka KakiyamaYakult Honsha Co., Ltd., Central Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-0012, Japan.
Yuh ShiwaDepartment of Molecular Microbiology, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.
Chiaki KagaYakult Honsha Co., Ltd., Central Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-0012, Japan.
Toshihide KobayashiYakult Honsha Co., Ltd., Central Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-0012, Japan.
Koji NomotoDepartment of Molecular Microbiology, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.
Naomi Harima-MizusawaYakult Honsha Co., Ltd., Central Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-0012, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of the relationships between the microbiota and intestinal environment of companion animals has gained increasing attention, particularly concerning health and disease. Previously, we demonstrated that continuous intake of galacto-oligosaccharides (GOS), a prebiotic, can improve the health of household dogs by modulating their gut microbiota. Given the potential health benefits of GOS in cats, we conducted a single-arm open-label study to evaluate the effects of a GOS-containing syrup on the gut microbiota and its metabolites in healthy cats. The study included 25 household cats and was conducted over 12 weeks. Each cat was fed 1.2 g of a GOS-containing syrup per day, equivalent to 0.5 g of GOS. Before the start of the study (week 0), during the 8-week intake period (weeks 4 and 8), and 4 weeks after the intake period (week 12), fecal microbiota, fecal organic acid and putrefactive product concentrations, fecal odor, and serum uremic toxin concentrations were assessed. The results showed that the levels of acetic acid-producing

Indexed as

Bifidobacteriaceaegalacto-oligosaccharideshousehold catsmicrobiotaorganic acidsPeptostreptococcaceaeuremic toxins

Identifiers

PMID40171393
PMCPMC11957758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.