Evidence map›Paper›PMID 40171227›Full record

ArticleFrontiers in cell and developmental biology2025

p75 neurotrophin receptor regulates craniofacial growth and morphology in postnatal development.

Byron Zhao, Jinsook Suh, Yan Zhang, Eric Yin, Chiho Kadota-Watanabe, In Won Chang, Jun Yaung, Isabelle Lao-Ngo, Nathan M Young, Reuben H Kim and 2 more

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Byron ZhaoDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.
Jinsook SuhDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.
Yan ZhangDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.
Eric YinDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.
Chiho Kadota-WatanabeDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.
In Won ChangShapiro Family Laboratory of Viral Oncology and Aging Research, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States.
Jun YaungShapiro Family Laboratory of Viral Oncology and Aging Research, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States.
Isabelle Lao-NgoDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.
Nathan M YoungDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, United States.
Reuben H KimShapiro Family Laboratory of Viral Oncology and Aging Research, School of Dentistry, University of California, Los Angeles, Los Angeles, CA, United States.
Ophir D KleinDepartment of Orofacial Sciences, Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, United States.
Christine HongDivision of Orthodontics, Department of Orofacial Sciences, University of California, San Francisco, San Francisco, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Craniofacial abnormalities are among the most prevalent congenital defects, significantly affecting appearance, function, and quality of life. While the role of genetic mutations in craniofacial malformations is recognized, the underlying molecular mechanisms remain poorly understood. In this study, we investigate the role of p75 neurotrophin receptor (p75

Indexed as

calvarial developmentCD271craniofacial developmentcraniofacial morphogenesisgeometric morphometric analysisNGFp75NTR

Identifiers

PMID40171227
PMCPMC11959563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.