Evidence map›Paper›PMID 40171204›Full record

ArticleAnnals of statistics2024

Minimax rates for heterogeneous causal effect estimation.

Edward H Kennedy, Sivaraman Balakrishnan, James M Robins, Larry Wasserman

Abstract read
In one paragraph

Article in Annals of statistics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Heterogeneity in associations between food insecurity and diabetes outcomes.Journal of epidemiology and community health · 2025
    Article
  2. Data fusion methods for the heterogeneity of treatment effect and confounding function.Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Causal isotonic calibration for heterogeneous treatment effects.Proceedings of machine learning research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edward H KennedyDepartment of Statistics & Data Science, Carnegie Mellon University.
Sivaraman BalakrishnanDepartment of Statistics & Data Science, Carnegie Mellon University.
James M RobinsDepartments of Biostatistics and Epidemiology, Harvard University.
Larry WassermanDepartment of Statistics & Data Science, Carnegie Mellon University.

Funding

Efficient nonparametric estimation of heterogeneous treatment effects in causal inferenceR01LM013361 · NLM · UNIVERSITY OF PENNSYLVANIA · PI KEELE, LUKE, KENNEDY, EDWARD H. · 2021 to 2025
$2.0M
NLM NIH HHS R01 LM013361
6 · The paper itself

Abstract

Estimation of heterogeneous causal effects - i.e., how effects of policies and treatments vary across subjects - is a fundamental task in causal inference. Many methods for estimating conditional average treatment effects (CATEs) have been proposed in recent years, but questions surrounding optimality have remained largely unanswered. In particular, a minimax theory of optimality has yet to be developed, with the minimax rate of convergence and construction of rate-optimal estimators remaining open problems. In this paper we derive the minimax rate for CATE estimation, in a Hölder-smooth nonparametric model, and present a new local polynomial estimator, giving high-level conditions under which it is minimax optimal. Our minimax lower bound is derived via a localized version of the method of fuzzy hypotheses, combining lower bound constructions for nonparametric regression and functional estimation. Our proposed estimator can be viewed as a local polynomial R-Learner, based on a localized modification of higher-order influence function methods. The minimax rate we find exhibits several interesting features, including a non-standard elbow phenomenon and an unusual interpolation between nonparametric regression and functional estimation rates. The latter quantifies how the CATE, as an estimand, can be viewed as a regression/functional hybrid.

Indexed as

causal inferencefunctional estimationhigher order influence functionsnonparametric regressionoptimal rates of convergence

Identifiers

PMID40171204
PMCPMC11960818

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.