ArticleFrontiers in endocrinology2025
Association between the stress hyperglycemia ratio and all-cause mortality in critically ill patients with T2DM: a retrospective study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Longitudinal Stress Hyperglycemia Trajectories and Severe Outcome in Patients Hospitalized for Viral Respiratory Infections: A 72-Hour Phenotyping Study.Diagnostics (Basel, Switzerland) · 2026Article
- Delayed Radiological Resolution: A Comparative Longitudinal Study of Viral Pneumonia Evolution in Diabetic vs. Non-Diabetic Patients.Diseases (Basel, Switzerland) · 2026Article
- The Diabetes-Viral Respiratory Syndemic: Pathophysiological Insights and Precision Management: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Article
- Early relative glycemic stress trajectories identify a high-risk metabolic phenotype in critically ill patients with atherosclerotic cardiovascular disease: a dual-cohort study.Frontiers in endocrinology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Previous studies have shown a significant correlation between the stress-hyperglycemia ratio (SHR) and mortality. However, it is unknown whether the SHR has the same predictive value in severely ill patients. The main purpose of this research was to investigate the association between the SHR and all-cause mortality in critically ill patients with T2DM. Methods: The data used in this study were derived from the Medical Information Mart for Intensive Care (MIMIC-IV) database. The primary outcome was 180-day mortality and the secondary outcomes were 28-day, 90-day and 365-day mortality. The main analytical methods included: Kaplan-Meier survival analysis, the COX proportional hazards model and restricted cubic splines. Results: A total of 993 patients were included. The 28-day, 90-day, 180-day, and 365-day mortalities reached 10.4%, 14.4%, 16.7% and 19.0%, respectively. Multivariate Cox proportional hazards analysis revealed that the elevated SHR was significantly related to 28-day, 90-day and 180-day all-cause mortality even after cofounder adjustment. Restricted cubic spline analysis revealed a nonlinear association between the SHR and the risk of 28-day (p for nonlinear=0.014), 90-day (p for nonlinear=0.007), 180-day (p for nonlinear=0.001) and 365-day (p for nonlinear=0.003) all-cause mortality. Conclusion: SHR is significantly associated with 28-day, 90-day and 180-day all-cause mortality in critically ill patients with T2DM. This may help us identify patients at higher risk of death early.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.