Evidence map›Paper›PMID 40171196›Full record

ReviewFrontiers in endocrinology2025

Oncocytic pituicytoma in a patient with Cushing's disease: a case report and narrative literature review.

Jing Li, Shuaiming Chen, Huiwen Tan, Yerong Yu, Ying Tang, Bowen Cai, Jianwei Li

Abstract readCase ReportsReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing Li *Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Shuaiming Chen *Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Huiwen TanDepartment of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Yerong YuDepartment of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Ying TangDepartment of Pathology, West China Hospital of Sichuan University, Chengdu, China.
Bowen CaiDepartment of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China.
Jianwei LiDepartment of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Posterior pituitary tumors (PPTs) are extremely rare, with fewer than 400 cases reported to date. In 2022, the World Health Organization (WHO) classified four types of tumors originating from the posterior pituitary: traditional pituicytoma, oncocytic pituicytoma, granular pituicytoma, and ependymal pituicytoma. To our knowledge, only one subject with coexistence of Cushing's disease and oncocytic pituicytoma (spindle cell oncocytoma) has been reported, but the clinical features of this patient were not described in detail. Case presentation: We presented a case of a patient with Cushing's syndrome and a pituitary mass. Transsphenoidal surgery was performed, and pathologic examination revealed two distinct tumors: a corticotroph adenoma with a diameter of less than 2 mm and a larger oncocytic pituicytoma. Post-surgery serum cortisol was 51 nmol/L, indicating complete remission. Corticotroph adenoma or corticotroph hyperplasia was identified after surgery in less than half of the subjects with Cushing's disease and PPT. Conclusions: Our study indicates that Cushing's disease in patients with PPT may be caused by the existence of collision lesions, with corticotroph adenoma or hyperplasia being difficult to detect due to their small dimensions.

Indexed as

Adenoma, OxyphilicPituitary ACTH HypersecretionPituitary Gland, PosteriorPituitary NeoplasmsACTH-Secreting Pituitary AdenomaHumansCushing’s diseaseoncocytic pituicytomapituitary adenomaposterior pituitary tumorsspindle cell oncocytoma

Identifiers

PMID40171196
PMCPMC11958162

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.