Evidence map›Paper›PMID 40171174›Full record

ArticleFrontiers in pediatrics2025

Efficacy and safety of extracorporeal membrane oxygenation combined with continuous renal replacement therapy in the management of pediatric acute respiratory distress syndrome.

Yufan Yang, Xiangni Wang, Xiulan Lu, Xinping Zhang, Jiaotian Huang, Zhenghui Xiao

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yufan Yang *Department of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.
Xiangni Wang *Department of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.
Xiulan LuDepartment of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.
Xinping ZhangDepartment of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.
Jiaotian HuangDepartment of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.
Zhenghui XiaoDepartment of Intensive Care Unit, The School of Pediatrics, Hengyang Medical School, University of South China (Hunan Children's Hospital), Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The efficacy and safety of combining extracorporeal membrane oxygenation with continuous renal replacement therapy remain controversial. This study aimed to evaluate the efficacy and safety of extracorporeal membrane oxygenation combined with continuous renal replacement therapy in the treatment of pediatric acute respiratory distress syndrome. Methods: This retrospective study, conducted at Hunan Children's Hospital between January 2019 and December 2023, included 30 pediatric patients with acute respiratory distress syndrome who underwent extracorporeal membrane oxygenation treatment. The patients were divided into two groups based on whether continuous renal replacement therapy was used during treatment: 21 in the extracorporeal membrane oxygenation with continuous renal replacement therapy group and nine in the extracorporeal membrane oxygenation-only group. The groups were compared using Results: This study included 19 (63.3%) male and 11 (36.7%) female patients (mean age: 63.33 ± 54.41 months). The ratios of arterial partial pressure of oxygen to fraction of inspired oxygen before and at withdrawal of extracorporeal membrane oxygenation were 58.50 (40.75-70.31) and 257.00 (113.25-358.33) mmHg, respectively ( Conclusions: The combination of extracorporeal membrane oxygenation and continuous renal replacement therapy provides safe and effective respiratory support for pediatric patients with severe acute respiratory distress syndrome and enables effective fluid-balance management, removal of inflammatory factors, and maintenance of electrolyte equilibrium.

Indexed as

acute respiratory distress syndromecontinuous renal replacement therapyextracorporeal membrane oxygenationpediatricsPICU (pediatric intensive care unit)

Identifiers

PMID40171174
PMCPMC11960717

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