Evidence map›Paper›PMID 40171166›Full record

ReviewFrontiers in cellular and infection microbiology2025

Viable but non-cultivable state in oral microbiota: a critical review of an underexplored microbial survival strategy.

Marzie Mahdizade Ari, Konstantin Johannes Scholz, Fabian Cieplik, Ali Al-Ahmad

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Microorganisms · 2026
    Review
  7. Article
  8. Review
  9. Site-stratified global oralJournal of oral microbiology · 2026
    Review
  10. Article
  11. Review
  12. BeyondMedicina (Kaunas, Lithuania) · 2025
    Review
  13. Towards EffectiveInternational journal of molecular sciences · 2025
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marzie Mahdizade AriDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Konstantin Johannes ScholzDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.
Fabian CieplikDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.
Ali Al-AhmadDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The viable but non-cultivable (VBNC) state and persister cells, two dormancy phenomena in bacteria, differ in various aspects. The entry of bacteria into the VBNC state as a survival strategy under stressful conditions has gained increasing attention in recent years, largely due to the higher tolerance of VBNC cells to antibiotics and antimicrobials resulting from their low metabolic activity. The oral cavity favors biofilm growth in dental hard tissues, resulting in tooth decay and periodontitis. Despite advances in VBNC state detection in the food industry and environment, the entry capability of oral bacteria into the VBNC state remains poorly documented. Furthermore, the VBNC state has recently been observed in oral pathogens, including

Indexed as

BacteriaMicrobial ViabilityMicrobiotaMouthAnti-Bacterial AgentsBacterial Physiological PhenomenaBiofilmsEnterococcus faecalisHumansPorphyromonas gingivalisAnti-Bacterial Agentsdetection methodsdormancyinfectious diseasespersister cellsresuscitationVBNCviable but non-cultivablevirulence

Identifiers

PMID40171166
PMCPMC11959090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.