Evidence map›Paper›PMID 40170989›Full record

ArticleCJC pediatric and congenital heart disease2025

Prenatal Detection of Wolff-Parkinson-White Syndrome Using the Atrioventricular Interval on Fetal Echocardiogram.

Pierre-Olivier Veillette, Emilia Beauchamp, Cecilia Gonzalez Corcia, Jean-Luc Bigras

Abstract read
In one paragraph

Article in CJC pediatric and congenital heart disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Pierre-Olivier VeilletteDepartment of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
Emilia BeauchampFaculty of Medicine, Université de Montréal, Montréal, Québec, Canada.
Cecilia Gonzalez CorciaDepartment of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
Jean-Luc BigrasDepartment of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fetal Doppler echocardiography has been widely used for the detection and characterization of fetal tachyarrhythmias. Doppler interrogation of the superior vena cava and the aorta (SVC-Ao) is used to determine the electrophysiological etiology of arrhythmias. The present study aims to investigate if the SVC-Ao technique in fetal echocardiograms could identify fetuses with Wolff-Parkinson-White (WPW) syndrome. Methods: We retrospectively searched for consecutive fetal echocardiograms with evidence of tachyarrhythmias performed at the CHU Sainte-Justine from January 2000 to July 2021. The primary outcome was defined as the presence of pre-excitation on postnatal electrocardiogram (ECG) in the context of a prenatal tachyarrhythmia and the identification of a short atrioventricular (AV) interval. Results: From a cohort of 69 patients presenting with fetal tachyarrhythmia diagnosed by echocardiography, AV intervals were measured in 9 fetuses (13%) that showed WPW on the postnatal surface ECG. The AV interval measured using fetal echocardiography showed a median of 107 ms (interquartile range: 104-116 ms), representing a Conclusions: Doppler echocardiographic AV interval measurements in fetuses with arrhythmias allow identification of prenatal WPW. The early diagnosis of WPW offers the possibility of a more comprehensive postnatal management plan, including the neonatology and cardiology teams, as well as preparing in advance for specific antiarrhythmic drug therapy.

Identifiers

PMID40170989
PMCPMC11955725

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