ArticleFrontiers in microbiology2025
RmmLII, a novel marine-derived
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Quorum sensing inhibition strategies for the control of Pseudomonas aeruginosa infections.World journal of microbiology & biotechnology · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Quorum sensing (QS) is a bacterial intercellular communication system that can regulate the expression of various virulence genes coordinate the group behaviors of the bacteria by sensing the concentration of signaling molecules in the surrounding environment. An increase in bacterial drug-resistance has been caused by the widespread use of antibiotics, making it urgent to identify safe and effective alternatives to antibiotics. Quorum quenching (QQ) is a strategy to control bacterial infections by disrupting the QS system, which reduces pathogenicity or increases biofilm susceptibility to antibiotics. Several natural agents with QQ activity have been identified, including small molecular inhibitors and QQ enzymes that disrupt bacterial QS by degrading or modifying the QS signal molecules. Methods: In the present study, We performed heterologous recombinant expression of the potential QQ enzyme-encoding gene Results: A novel Discussion: This study demonstrates the potential application of RmmLII in controlling PAO1 infections, offering new insights for the development of novel antibiotic alternatives. RmmLII has the potential as a therapeutic agent for application in the mitigating PAO1 infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.