Evidence map›Paper›PMID 40170892›Full record

ReviewFrontiers in neurology2025

Physical activity and gait in patients with idiopathic normal pressure hydrocephalus: a literature review.

Kathrin Oebel, Tobias Moeller, Julie Etingold, Till Brombach, Sana Aslam, Justin L Hoskin, Yonas E Geda, Alexander Woll, Janina Krell-Roesch

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathrin OebelInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Tobias MoellerInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Julie EtingoldDepartment of Neurosurgery, Klinikum Karlsruhe, Karlsruhe, Germany.
Till BrombachDepartment of Neurosurgery, Klinikum Karlsruhe, Karlsruhe, Germany.
Sana AslamDepartment of Neurology, University of Colorado, Denver, CO, United States.
Justin L HoskinDepartment of Neurology, Barrow Neurological Institute, Phoenix, AZ, United States.
Yonas E GedaDepartment of Neurology, Barrow Neurological Institute, Phoenix, AZ, United States.
Alexander WollInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Janina Krell-RoeschInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Idiopathic normal pressure hydrocephalus (iNPH) is characterized by impaired gait and cognition, and urinary incontinence. Even though iNPH still lacks standardized diagnostic criteria, many patients may potentially benefit from treatment which are often invasive procedures. Objectives: To provide an overview of the current state of research on physical activity behavior and gait in patients with iNPH, and examine potential changes after treatment (i.e., shunt surgery, spinal tap test or lumbar drainage). Methods: This literature review was carried out based on the PRISMA statement and we searched PubMed, Web of Science and Scopus databases in April 2023. Results: In total, 32 studies were included: 29 focusing on gait, 2 focusing on gait and physical activity, and 1 focusing on physical activity. All studies reported improvements in gait, such as reduced gait ataxia or shuffling gait and greater variability of gait cycle length, after an intervention or treatment. Improvements may depend on patients' age, symptom duration, and treatment method, among others. Conclusion: Improvements in gait after iNPH treatment (e.g., shunt surgery) are well documented, whereas results on physical activity behavior in iNPH patients are inconsistent. More research on physical activity and gait outcomes before and after treatment is needed, also with regard to treatment success.

Indexed as

CSF shunt surgerydilated cerebral ventriclesgaitHakim’s triadidiopathic normal pressure hydrocephalusphysical activity

Identifiers

PMID40170892
PMCPMC11959003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.