ArticleOTA international : the open access journal of orthopaedic trauma2025
Muscle injury in orthopaedic trauma.
Article in OTA international : the open access journal of orthopaedic trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Alginate-encapsulated muscle-derived stem cell spheroids promote muscle regeneration in a murine model of volumetric muscle loss.Frontiers in pharmacology · 2025Article
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Authors and funding
6 authors.
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Abstract
Muscle injury in the setting of orthopaedic trauma is common. Skeletal muscle injury can cause immune dysregulation and impair fracture healing both in patients and in various preclinical models. Muscle injury can also be associated with impaired vascularity and eliminate the muscle paracrine effect, both of which can impair fracture healing. Severe muscle injury can lead to volumetric muscle loss. While there are currently no effective treatments for volumetric muscle loss, minced muscle autograft has been shown to improve fracture healing, but not improve muscle function. Acute compartment syndrome can severely impact functional recovery and limit fracture healing. However, current animal models of compartment syndrome lack appropriate translation to the clinical injury.
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