Evidence map›Paper›PMID 40170838›Full record

SynthesisFrontiers in immunology2025

Limitations of nomogram models in predicting survival outcomes for glioma patients.

Jihao Xue, Hang Liu, Lu Jiang, Qijia Yin, Ligang Chen, Ming Wang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Development and validation of nomograms to predict brain metastasis-free survival in lung and breast cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jihao Xue *Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
Hang Liu *Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
Lu Jiang *Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
Qijia Yin *Department of Urology or Nursing, Dazhou First People's Hospital, Dazhou, Sichuan, China.
Ligang ChenDepartment of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
Ming WangDepartment of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Glioma represents a prevalent and malignant tumor of the central nervous system (CNS), and it is essential to accurately predict the survival of glioma patients to optimize their subsequent treatment plans. This review outlines the most recent advancements and viewpoints regarding the application of nomograms in glioma prognosis research. Design: With an emphasis on the precision and external applicability of predictive models, we carried out a comprehensive review of the literature on the application of nomograms in glioma and provided a step-by-step guide for developing and evaluating nomograms. Results: A summary of thirty-nine articles was produced. The majority of nomogram-building research has used limited patient samples, disregarded the proportional hazards (PH) assumption in Cox regression models, and some of them have failed to incorporate external validation. Furthermore, the predictive capability of nomograms is influenced by the selection of incorporated risk factors. Overall, the current predictive accuracy of nomograms is moderately credible. Conclusion: The development and validation of nomogram models ought to adhere to a standardized set of criteria, thereby augmenting their worth in clinical decision-making and clinician-patient communication. Prior to the clinical application of a nomogram, it is imperative to thoroughly scrutinize its statistical foundation, rigorously evaluate its accuracy, and, whenever feasible, assess its external applicability utilizing multicenter databases.

Indexed as

Brain NeoplasmsGliomaNomogramsHumansPrognosiscox regression modelgliomanomogrampredictionproportional hazards (PH) assumption

Identifiers

PMID40170838
PMCPMC11959071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.