SynthesisClinics in orthopedic surgery2025
Comparison of Analgesic Efficiency between Local Infiltration of a Long-Acting Analgesic and Regional Nerve Block among Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction: Meta-Analysis of Randomized Controlled Trials.
Synthesis in Clinics in orthopedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Arthroscopic anterior cruciate ligament (ACL) reconstruction is gaining popularity. Different kinds of anesthetic techniques are used; however, regional nerve block (RNB) such as femoral nerve block is considered the most popular choice. The purpose of this study was to compare the effectiveness of long-acting local anesthesia infiltration (LAI) versus RNB used to control pain and reduce opioid consumption in patients undergoing arthroscopic ACL reconstruction. Methods: We conducted a meta-analysis using a comprehensive literature search of Google Scholar, PubMed, Medline, and Cochrane Library. All randomized trials comparing the use of infiltration anesthesia versus RNB in patients undergoing arthroscopic ACL reconstruction were included. Methodological quality, risk of bias, and grade of the eligible studies were assessed by 3 independent reviewers. The risk of bias was analyzed using contour-enhanced funnel plots. Results: The search yielded 671 records. Eight studies were included in the systematic review. The study focused on the assessment of immediate, 24-hour, and 48-hour postoperative pain scores and total opioid consumption. There was no significant difference between the use of LAI and RNB with regard to the immediate ( Conclusions: Regarding postoperative pain control, LAI showed similar clinical effects when compared to the conventional RNB, while maintaining a similar level of opioid consumption postoperatively, decreasing the risk of any adverse effects of morphine. In summary, LAI offers a simpler method of achieving pain relief without the motor weakness associated with RNB. It also allows surgeons to perform ACL reconstruction in institutions without specialized anesthesia for RNB.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.