Evidence map›Paper›PMID 40170669›Full record

Trial reportPsychological medicine2025

Capitalizing on natural language processing (NLP) to automate the evaluation of coach implementation fidelity in guided digital cognitive-behavioral therapy (GdCBT).

Nur Hani Zainal, Regina Eckhardt, Gavin N Rackoff, Ellen E Fitzsimmons-Craft, Elsa Rojas-Ashe, Craig Barr Taylor, Burkhardt Funk, Daniel Eisenberg, Denise E Wilfley, Michelle G Newman

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nur Hani ZainalDepartment of Psychology, National University of Singapore (NUS), Singapore.ORCID 0000-0002-2023-3173
Regina EckhardtTechnical University of Munich, TUM School of Life Sciences, Freising, Germany.
Gavin N RackoffDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA.ORCID 0000-0003-3525-3975
Ellen E Fitzsimmons-CraftDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-7064-3835
Elsa Rojas-AsheDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-8563-3696
Craig Barr TaylorDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Burkhardt FunkDepartment of Information Systems and Data Science, Leuphana University Lüneburg, Lüneburg, Germany.ORCID 0000-0001-5855-2666
Daniel EisenbergFielding School of Public Health, University of California at Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-5597-7925
Denise E WilfleyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Michelle G NewmanDepartment of Psychology, The Pennsylvania State University, University Park, PA, USA.ORCID 0000-0003-0873-1409

Funding

Harnessing Mobile Technology to Reduce Mental Health Disorders in College PopulationsR01MH115128 · NIMH · WASHINGTON UNIVERSITY · PI EISENBERG, DANIEL, NEWMAN, MICHELLE G · 2018 to 2022
$4.1M
Developing an Optimized Conversational Agent or "Chatbot" to Facilitate Mental Health Services Use in Individuals with Eating DisordersK08MH120341 · NIMH · WASHINGTON UNIVERSITY · PI FITZSIMMONS-CRAFT, ELLEN E. · 2019 to 2023
$824k
NIMH NIH HHS K08 MH120341NIMH NIH HHS R01 MH115128
6 · The paper itself

Abstract

backgroundAs the use of guided digitally-delivered cognitive-behavioral therapy (GdCBT) grows, pragmatic analytic tools are needed to evaluate coaches' implementation fidelity.

aimsWe evaluated how natural language processing (NLP) and machine learning (ML) methods might automate the monitoring of coaches' implementation fidelity to GdCBT delivered as part of a randomized controlled trial.

methodCoaches served as guides to 6-month GdCBT with 3,381 assigned users with or at risk for anxiety, depression, or eating disorders. CBT-trained and supervised human coders used a rubric to rate the implementation fidelity of 13,529 coach-to-user messages. NLP methods abstracted data from text-based coach-to-user messages, and 11 ML models predicting coach implementation fidelity were evaluated.

resultsInter-rater agreement by human coders was excellent (intra-class correlation coefficient = .980-.992). Coaches achieved behavioral targets at the start of the GdCBT and maintained strong fidelity throughout most subsequent messages. Coaches also avoided prohibited actions (e.g. reinforcing users' avoidance). Sentiment analyses generally indicated a higher frequency of coach-delivered positive than negative sentiment words and predicted coach implementation fidelity with acceptable performance metrics (e.g. area under the receiver operating characteristic curve [AUC] = 74.48%). The final best-performing ML algorithms that included a more comprehensive set of NLP features performed well (e.g. AUC = 76.06%).

conclusionsNLP and ML tools could help clinical supervisors automate monitoring of coaches' implementation fidelity to GdCBT. These tools could maximize allocation of scarce resources by reducing the personnel time needed to measure fidelity, potentially freeing up more time for high-quality clinical care.

Indexed as

Anxiety DisordersCognitive Behavioral TherapyFeeding and Eating DisordersMachine LearningMentoringNatural Language ProcessingAdultFemaleHumansMaleanxietydepressiondigital mental health interventioneating disordersguided internet-delivered cognitive-behavioral therapyimplementation fidelitymachine learningnatural language processing

Identifiers

PMID40170669
PMCPMC12094662

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.