Observational studyDiabetes technology & therapeutics2025
Real-Life Performance of Automated Insulin Delivery Systems for High-Carbohydrate Meals: Are All Systems the Same?
Observational study in Diabetes technology & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- A systematic literature review and meta-analysis of real-world evidence on commercially available automated insulin delivery systems in people with type 1 diabetes.Diabetes, obesity & metabolism · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Managing postprandial blood glucose levels in children and adolescents with type 1 diabetes remains challenging, particularly with high-carbohydrate meals. This study analyzed postprandial glycemic responses to Margherita pizza and a ham sandwich with similar macronutrient content in children using two different automated insulin delivery (AID) systems: MiniMed™ 780G and Tandem t:slim X2™ with Control-IQ. Thirty-four participants consumed both meals on separate occasions while maintaining standard insulin boluses. Results showed no significant differences in glycemic control between meals, suggesting that Margherita pizza can be effectively managed with standard bolus strategies. However, individuals using MiniMed 780G demonstrated a higher time in target range (70-140 mg/dL) in the 10 h following pizza consumption compared with Control-IQ users, possibly due to MiniMed 780G's multiple automatic correction boluses. No other significant differences in glucometrics or insulin delivery were observed. These findings highlight the need for personalized meal management strategies based on specific AID system algorithms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.