Evidence map›Paper›PMID 40170580›Full record

ArticleAnnals of laboratory medicine2025

Adjustment Formula for Harmonizing Triglyceride Values in the Korea National Health and Nutrition Examination Survey, 2005-2022.

Rihwa Choi, Jong Do Seo, Eun-Jung Cho, Woochang Lee, Yeo-Min Yun

Abstract read
In one paragraph

Article in Annals of laboratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rihwa ChoiDepartment of Laboratory Medicine, Green Cross Laboratories (GC Labs), Yongin, Korea.ORCID https://orcid.org/0000-0002-8266-2248
Jong Do SeoDepartment of Laboratory Medicine, Konkuk University Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-7449-7978
Eun-Jung ChoDepartment of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.ORCID https://orcid.org/0000-0003-1907-9639
Woochang LeeDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3956-6397
Yeo-Min YunDepartment of Laboratory Medicine, Konkuk University Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-5485-8331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Korea National Health and Nutrition Examination Survey (KNHANES) triglyceride testing changed from the glycerol blanking method (2005-2021) to the glycerol nonblanking method (2022). We converted triglyceride data from 2005-2021 to that obtained since 2022 with different analytical methods. Methods: To develop a conversion equation, 98 fresh serum specimen pairs were compared using Passing-Bablok regression analysis. Implications of the conversion equation on epidemiological data were evaluated using KNHANES data from 2019-2021. Bias estimations determined using the Lipid Standardization Program (LSP) of the United States Centers for Disease Control and Prevention (CDC) enhanced the accuracy and comparability of the triglyceride results. Results: Triglyceride concentrations measured via the glycerol non-blanking method were 10.7 mg/dL (0.12 mmol/L, 10.0%) higher than those from the glycerol blanking method, with a 9.9 mg/dL (0.11 mmol/L, 5.0%) difference at a concentration of 200 mg/dL (2.26 mmol/L, N=98). The conversion equation Conclusions: KNHANES triglyceride values in 2022 (non-blanking) were substantially higher than those from 2005-2021 (blanking). Conversion equations helped effectively adjust 2005-2021 data. Researchers should consider adjusting the KNHANES triglyceride data based on their study characteristics.

Indexed as

TriglyceridesAdultFemaleGlycerolHumansMaleMiddle AgedNutrition SurveysRegression AnalysisRepublic of KoreaGlycerolTriglyceridesCalibrationData ProcessingKorea National Health and Nutrition Examination SurveyStandardizationTriglycerides

Identifiers

PMID40170580
PMCPMC11996691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.