ArticleThe Journal of clinical endocrinology and metabolism2025
Characterizing Disparities in Access to Surgery for Pituitary Adenomas: A National Cancer Database Analysis.
Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prediction of recurrence after surgery for pituitary adenoma using machine learning- based models: systematic review and meta-analysis.BMC endocrine disorders · 2025Pooled it
- Racial and ethnic differences in presentation and postoperative recovery after transsphenoidal surgery for cushing disease.Journal of neuro-oncology · 2026Article
- Geographic distribution of medicare fee-for-service pituitary surgery providers is associated with community-level social vulnerability and access barriers.Journal of neuro-oncology · 2026Article
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Authors and funding
14 authors.
Funding
Abstract
contextAlthough there is an established improved postoperative outcome for pituitary adenomas (PA) surgically resected at high-volume facilities (HVFs), access to these centers may not be equitable.
objectiveTo investigate the racial and socioeconomic differences that lead to unequal distribution of access for PAs at HVFs in the United States. DESIGN AND PATIENTS: Retrospective analysis of data from the National Cancer Database from 2004 to 2019 on 57 807 patients with PA.
main outcome measuresBaseline description of patients treated at HVFs, survival outcomes, and predictors of survival were evaluated in patients with PA.
resultsA total of 47.6% (n = 27 523) underwent surgery at a HVF. On multivariable analysis, African-American race [odds ratio (OR): 0.89, P < .001] and Hispanic ethnicity (OR: 0.80, P < .001) had significantly lower odds of having a surgical procedure at a HVF as compared to a reference Caucasian population. Patients from rural locations (OR: 0.79, P = .003; reference = urban); with Medicaid insurance (OR: 0.86, P < .001; reference = private), those with lower income [<$40 227 (OR: 0.93, P = .049); reference = ≥$63 333], and patients from zip codes with large percentages of adults who did not graduate high school [≥17.6% (OR: 0.95, P < .001); reference = <6.3%] were significantly less likely to have surgery at a HVF. An increasing trend in access to surgical care at HVFs for PA patients over time was demonstrated [eg, 2005 (OR = 1.10 [0.97-1.26], P = .173) vs 2019 (OR = 1.27 [1.13-1.43], P < .001)].
conclusionThere are significant racial and socioeconomic disparities in access to HVFs for adult patients seeking surgical resection of pituitary adenomas.
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