Evidence map›Paper›PMID 40170502›Full record

ArticleScience progress

The synaptic availability of GluA1 is reduced in hippocampal neurons of a murine model of dynamin-2 linked autosomal dominant centronuclear myopathy.

Carolina Flores-Muñoz, Marjorie Labraña-Allende, Michelle Mattar-Araos, Barbara Gomez-Soto, Joaquin Silva-Guzman, Lorena Prado-Vega, Jorge Arriagada-Díaz, María Jose Guerra-Fernández, Jorge A Bevilacqua, Marc Bitoun and 3 more

Abstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carolina Flores-MuñozCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.ORCID 0000-0001-5472-8521
Marjorie Labraña-AllendeCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.
Michelle Mattar-AraosCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.
Barbara Gomez-SotoCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.
Joaquin Silva-GuzmanCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.
Lorena Prado-VegaPrograma de Magister en Ciencias, Mención Neurociencia, Universidad de Valparaíso, Valparaíso, Chile.
Jorge Arriagada-DíazPrograma de Magister en Ciencias, Mención Neurociencia, Universidad de Valparaíso, Valparaíso, Chile.ORCID 0000-0001-7078-0741
María Jose Guerra-FernándezCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.ORCID 0009-0004-0268-0983
Jorge A BevilacquaDepartamento de Neurología y Neurocirugía, Hospital Clínico Universidad de Chile, Facultad de Medicina, Universidad de Chile, Santiago, Chile.ORCID 0000-0002-0525-9308
Marc BitounSorbonne Université, Inserm, Institut de Myologie, Centre de Recherche en Myologie, Paris, France.ORCID 0000-0002-4188-7918
Ana M CárdenasCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.ORCID 0000-0002-8747-4916
Alvaro O ArdilesCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.ORCID 0000-0001-8295-2133
Arlek M Gonzalez-JamettCentro Interdisciplinario de Neurociencia de Valparaíso, CINV, Valparaíso, Chile.ORCID 0000-0003-2357-0260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveAutosomal dominant centronuclear myopathy (AD-CNM) is a neuromuscular congenital disease caused by mutations in the

Indexed as

Dynamin IIHippocampusMyopathies, Structural, CongenitalNeuronsReceptors, AMPASynapsesAnimalsDisease Models, AnimalMiceMice, TransgenicMutationSynaptic TransmissionDNM2 protein, mouseDynamin IIReceptors, AMPAautosomal dominant centronuclear myopathyDynamin-2glutamate-AMPA receptors

Identifiers

PMID40170502
PMCPMC11963778

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.