ArticleMedical physics2025
Imaging system for real-time, full-field pulse-by-pulse surface dosimetry of UHDR electron beams.
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- FLASH radiotherapy at a crossroads: a bibliometric perspective on progress and challenges.Discover oncology · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe interest in ultra-high dose rate (UHDR) radiation therapy (RT) has grown due to its potential to spare normal tissue. However, clinical application is hindered by dosimetry challenges, as current irradiators and dosimeters are not designed for UHDR's high fluence. To ensure safe treatment and accurate dose delivery, real-time dose and dose rate quantification methods are essential. PURPOSE: We propose a novel scintillation imaging system for in vivo, pulse-by-pulse surface dose monitoring during delivery with a UHDR-capable Mobetron (IntraOp LLC Sunnyvale, CA, USA) system. This setup aims to measure entrance beam dose with high 2D spatial and temporal resolution.
methodsA modified collimating cone was 3D printed to house the imaging lens. The system featured a 90° sinuscope endoscope attached to a CMOS camera, was gated by the Mobetron's magnetron output signal, and captured light from a scintillator placed on the treatment surface. Three scintillator types were tested for their emission intensity and decay time. Dose and dose rate linearity studies were performed using various pulse lengths and repetition frequencies, respectively, and the imaging data were compared to an EDGE diode detector (SunNuclear Melbourne, FL, USA) and the Mobetron beam-current transformer (BCT) measurements.
resultsDose (R
conclusionsThe developed imaging system met the criteria for measuring entrance beam dose with high spatial and temporal resolution, offering a promising in vivo dosimetry method for UHDR RT in preclinical and clinical trials.
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