Evidence map›Paper›PMID 40170276›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2025

Relationship Between Structure and Age in Healthy Achilles Tendons.

Kayla D Seymore, Shawn L Hanlon, Ryan T Pohlig, Dawn M Elliott, Karin Grävare Silbernagel

Abstract read
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Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kayla D SeymoreDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.ORCID 0000-0003-3125-2238
Shawn L HanlonDepartment of Kinesiology, California State University, Fullerton, California, USA.ORCID 0000-0002-5866-9853
Ryan T PohligDepartment of Epidemiology, University of Delaware, Newark, Delaware, USA.ORCID 0000-0002-8385-8218
Dawn M ElliottDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.ORCID 0000-0003-4792-1029
Karin Grävare SilbernagelDepartment of Physical Therapy, University of Delaware, Newark, Delaware, USA.ORCID 0000-0001-7566-407X

Funding

Recovery of symptoms, function, tendon structure and mechanical properties in patients with Achilles Tendinopathy: A comparison between men and womenR01AR072034 · NIAMS · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2018 to 2022
$2.5M
continuous shear wave elastography as a diagnostic marker for tendinopathyR21AR067390 · NIAMS · UNIVERSITY OF DELAWARE · PI CORTES CORREALES, DANIEL HUMBERTO, GRAVARE SILBERNAGEL, KARIN M E · 2015 to 2016
$322k
Assessment of Achilles Tendon Injury in AdolescentsF31AR081663 · NIAMS · UNIVERSITY OF DELAWARE · PI SEYMORE, KAYLA · 2023 to 2024
$81k
NIAMS NIH HHS F31 AR081663NIAMS NIH HHS R01 AR072034NIAMS NIH HHS R21 AR067390Research reported in this dissertation was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under award numbers R21AR067390, R01AR072034 and F31AR081663, in addition to the National Athletic Trainers' Association Research Foundation Doctoral Grant under award number 1920DGP08 and the Eastern Athletic Trainers' Association under award number 001_2021.
6 · The paper itself

Abstract

Age is an important factor to consider with Achilles tendon injury, as variability in tendon structure during developmental growth and aging influence lower limb function and mobility. However, the overlap in structural alterations with aging and Achilles tendon injury makes it unclear which structural changes are related to age separate from tendon pathology. The objective of this study was to determine the relationship between structure and age in healthy Achilles tendons. Healthy Achilles tendons from 389 children and adults (8-79 years) were included in this retrospective analysis. Achilles tendon morphology was assessed via B-mode ultrasound of Achilles tendon length, cross-sectional area (CSA), and thickness. Mechanical properties of Achilles tendon shear modulus and viscosity were assessed via continuous shear wave elastography. The relationship between Achilles tendon structure and age was determined using General Linear Models and White's test of heteroscedasticity (to assess for unequal variance across the age span), controlling for sex, weight, and physical activity level. Healthy free Achilles tendon length (p = 0.002), thickness (p < 0.001), CSA (p < 0.001), and viscosity (p = 0.009) increased with age, supporting age-related changes in tendon structure that may limit its capacity to store and transfer energy in older adults. Full Achilles tendon length and CSA varied across the age span (p < 0.05), suggesting the Achilles tendon undergoes natural aging processes seen with most musculoskeletal tissue. Normative data on Achilles tendon structure with age will contribute to our understanding and interpretation of Achilles tendon injury pathogenesis; aiding in the design of injury prevention and treatment strategies.

Indexed as

Achilles TendonAgingAdolescentAdultAgedAge FactorsChildFemaleHumansMaleMiddle AgedRetrospective StudiesUltrasonographyViscosityYoung AdultAchilles tendonmechanical propertiesolder adultspediatricultrasound

Identifiers

PMID40170276
PMCPMC12288136

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