ArticleBMC surgery2025
Surgical site infection rate in spine surgery, incidence, and risk factors: a ten-year retrospective cohort review in a developing neurosurgical centre.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Minimally invasive tubular decompression versus traditional open surgery for lumbar spinal stenosis: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- RCT-based meta-analysis of povidone-iodine irrigation in spinal surgery: clarifying efficacy and safety.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Clinical burden and treatment pathways of early deep surgical site infection after lumbar spine surgery: a Vietnamese single-center descriptive study.Journal of spine surgery (Hong Kong) · 2026Article
- Degradation-tunable coating with sustained silver release for spinal implants to prevent postoperative infections.Bioactive materials · 2026Article
- Factors associated with transfusion and surgical site infection following paediatric scoliosis surgery: insights from a Latin American retrospective cohort.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Late-onset Spinal Infection Caused byPlastic and reconstructive surgery. Global open · 2026Article
- Two-Year Outcomes of Postoperative Spine Infection: Implant Retention and Predictors of Treatment Failure.Open forum infectious diseases · 2026Article
- Incidence, microbiological spectrum, and antimicrobial resistance patterns of surgical site infections at a tertiary care hospital in Pakistan: a retrospective observational study.BMC infectious diseases · 2026Observational
- Early Discontinuation of Prophylactic Antibiotics Is Not Associated with Increased Surgical Site Infection Risk in Spine Surgery: A Nationwide Cohort Study.Antibiotics (Basel, Switzerland) · 2026Article
- Minimally Invasive Stabilization Versus Open Surgery for Spinal Metastases: A Retrospective Study Utilizing Propensity Score Matching and Weighting Sensitivity Analyses.Journal of clinical medicine · 2026Article
- Systemic immune responses in patients with spine surgery related infections.Frontiers in immunology · 2026Article
- Surgical humidification (HumiGard™) improves tissue temperature during open spinal surgery: a first in-human randomised controlled trial.Journal of spine surgery (Hong Kong) · 2025Article
- ERAS-guided matrix nursing pathway targeting risk factors in spine surgery: development and prospective evaluation.Frontiers in medicine · 2025Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectiveSurgical site infection (SSI) is the third common complication in spinal surgery and often results in poor clinical outcomes, prolonged hospital stays, and additional costs. This study estimated the incidence of SSI and identified risk factors in spine surgeries done within 10 years. METHODOLOGY: This was a retrospective cohort review of all patients who had spine surgery between January 2014 and December 2023. Patients' hospital records were retrieved, and relevant biodata and clinical information were obtained and entered into the Statistical Product and Service Solutions version 25. The incidence of SSI was computed and presented as a percentage, and a multivariable analysis to assess risk factors for SSI was done using the chi-square test and Fisher's exact test. The level of significance was set at a p-value < 0.05 and a 95% Confidence Interval.
resultsThe incidence of SSI was 11.7%; (24/206), predominantly caused by Staphylococcus Aureus (37.5%,P = 0.01) and largely (70%) occurred among patients admitted ≤ 48 h before surgery. The majority were superficial incisional SSIs (19/24,79.2%). They occurred commonly among patients operated for spondylotic disease (13/67,19.4%) and bacterial spondylitis (one out of the two patients) compared to the other spinal pathologies (p = 0.042). Similarly, infection rates were significantly higher in surgeries performed at the lumbar (14/63,22.2%) and thoracolumbar junction (4/31, 12.9%) compared to the cervical and thoracic spine (p = 0.009). This was found to increase the odds of developing SSI by 2.2 times (odds ratio: 2.20;CI:1.38-3.47, P = 0.001), The median duration of hospital stay was 36.5 days for patients with SSIs versus 23 days for patients without SSI (p = 0.008).
conclusionThis study found a relatively high incidence of SSI, which was predominantly superficial incisional SSI, caused by Staphylococcus Aureus, particularly among patients admitted within 48 h before surgery. Significant risk factors for these infections are patients operated on for spondylotic disease and those who had lumbar or thoracolumbar spine surgeries.
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