Evidence map›Paper›PMID 40170041›Full record

SynthesisBMC oral health2025

Vitamin D deficiency and oral health: a systematic review of literature.

Saida Ziada, Aws Wishahe, Najet Mabrouk, Souad Sahtout

Abstract readSystematic Review
In one paragraph

Synthesis in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saida ZiadaDepartment of Restorative Dentistry and Endodontics, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia. saidaziada@gmail.com.
Aws WishaheDepartment of Restorative Dentistry and Endodontics, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia.
Najet MabroukDepartment of Restorative Dentistry and Endodontics, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia.
Souad SahtoutDepartment of Restorative Dentistry and Endodontics, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D (VD) levels are gaining increasing interest in dentistry due to their association with several oral diseases.

objectiveThis study aimed to evaluate the relationship between vitamin D deficiency and various oral disorders. MATERIALS AND

methodsA broad search on the MEDLINE database via the PubMed interface and on the Spring Link platform was carried out using keywords related to the subject. An additional electronic search of gray literature was conducted via Google Scholar. Inclusion criteria were listed for the selection of articles and a reading grid was designed for the extraction of data relating to the research question. The quality of included studies was assessed using JBI's critical appraisal tools.

resultsA total of 57 studies were identified. After reading the full text, 16 studies were included and selected for qualitative analysis. There is an association between vitamin D deficiency and different oral disorders. Indeed, ten publications assessed the association between vitamin deficiency and periodontal disease, three examined the relationship between vitamin D deficit and dental caries, and one examined the intriguing relationship between vitamin D deficiency and tooth mineralization and two articles interested in vitamin D deficiency and stomatitis.

conclusionThe analysis of these selected articles shows that Vitamin D deficiency can lead to various oral health disorders during growth and adulthood. Indeed, it can be linked to tooth mineralization defects and increasing the risk of dental caries. Severe Vitamin D deficiency also increases the prevalence of periodontitis and gingival inflammation. It may also be linked to certain oral pathology entities, such as oral cancers and jaw osteonecrosis.

Indexed as

Mouth DiseasesOral HealthVitamin D DeficiencyDental CariesHumansPeriodontal DiseasesDental cariesOral cancerOral healthPeriodontitisTooth defectsVitamin D deficiency

Identifiers

PMID40170041
PMCPMC11959803

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.