Evidence map›Paper›PMID 40170033›Full record

ArticleBMC veterinary research2025

Preliminary study on the effects of dry powder and water extract of Neolamarckia cadamba on growth performance, immunity, and intestinal health of yellow-feathered broilers.

Yuxuan Wang, Guoping Chen, Changsong Liu, Yunxin Liao, Limin Wei, Hailong Wang, Junyi Luo, Jiajie Sun, Qianyun Xi, Yongliang Zhang and 1 more

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Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Investigating the role of the mPGES-PGE₂-EP4 pathway inFrontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuxuan Wang *College of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Guoping Chen *College of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Changsong Liu *Zhangzhou Yiyuan Bio-technology Co., Ltd., Longhai, Fujian, 363100, China.
Yunxin LiaoCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Limin WeiHainan Key Laboratory of Tropical Animal Breeding and Epidemic Research, Institute of Animal Husbandry and Veterinary Research, Hainan Academy of Agricultural Sciences, Haikou, 571100, Hainan, China.
Hailong WangCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Junyi LuoCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Jiajie SunCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Qianyun XiCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Yongliang ZhangCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China. zhangyl@scau.edu.cn.
Ting ChenCollege of Animal Science, Guangdong Province Key Laboratory of Animal Nutritional Regulation, National Engineering Research Center for Breeding Swine Industry, State Key Laboratory of Livestock and Poultry Breeding, South China Agricultural University, Guangzhou, 510642, Guangdong, China. allinchen@scau.edu.cn.

Funding

National broiler industry technology system project CARS-41-Z12National Key Research and Development Program of China 2022YFD1300904Natural Science Foundation of Guangdong Province 2021A1515011310Natural Science Foundation of Guangdong Province 2023A1515012127
6 · The paper itself

Abstract

backgroundIn recent years, the livestock industry has shown increasing concern regarding the need to find effective alternatives to antibiotic products while also striving to produce high-quality livestock and poultry products. Woody feed sources exhibit wide distribution and variety, containing a variety of bioactive substances such as flavonoids and alkaloids. Among these woody plants, Neolamarckia cadamba (Nc) has the characteristics of high leaf yield, fast growth rate, and rich nutritional value, which has great development potential. However, whether Nc supplementation can improve growth performance, immunity, and gut health of yellow-feathered broilers remains to be explored. In the present study, we aimed to investigate the effects of diet supplemented with dry powder or water extract of Nc on the growth performance, immunity, and intestinal health of yellow-feathered broilers.

resultsThe results showed that, (1) There was no significant difference in Body weight (BW), Average daily gain (ADG), Average daily feed intake (ADFI), and Feed conversion ratio (FCR) between the Nc experimental groups and the control group (P > 0.05); (2) Compared to the control group, the thymus index at 63 days was significantly increased in the 1% Nc dry powder group (P < 0.05). Conversely, the bursa index of Fabricius was significantly decreased (P < 0.05) in the same group; (3) Compared to the control group and antibiotic group, there were no significant differences in the serum levels of albumin (ALB), globulin (GLB), total protein (TP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and triglycerides (TG) in each experimental group (P > 0.05); (4) Compared to the control group, serum IgG levels were significantly increased in both the 1% Nc dry powder group and the 0.05% water extract group (P < 0.05); (5) Compared to the control group, 0.05% Nc water extract could significantly increase the mRNA expression levels of ZO-1 and TGF-β4 in the jejunum, as well as claudin-1, ZO-1, and TGF-β4 mRNA in the ileum(P < 0.05). Furthermore, the use of 1% Nc dry powder also resulted in a significant increase in the mRNA expression levels of TGF-β4 in the jejunum and ZO-1 mRNA in the ileum (P < 0.05).

conclusionsThese results suggest that the dietary supplementation with Nc can enhance immune function, improve small intestinal barrier integrity, and reduce intestinal inflammation to a certain extent. Among the four doses (1% dry powder, 2% dry powder, 0.05% water extract and 0.1% water extract), 1% dry powder and 0.05% water extract were more effective. These findings underscore the importance of exploring alternative feed additives in livestock production, as they may offer a viable strategy for promoting animal health and performance in the absence of traditional antibiotics.

Indexed as

ChickensIntestinesPlant ExtractsAnimal FeedAnimalsDietDietary SupplementsMalePowdersPlant ExtractsPowdersGrowth performanceImmunityIntestinal healthNeolamarckia cadambaYellow-feathered broiler

Identifiers

PMID40170033
PMCPMC11963628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.