Evidence map›Paper›PMID 40169887›Full record

ArticleEye (London, England)2025

Chat GPT vs an experienced ophthalmologist: evaluating chatbot writing performance in ophthalmology.

Gabriel Katz, Ofira Zloto, Avner Hostovsky, Ruth Huna-Baron, Iris Ben-Bassat Mizrachi, Zvia Burgansky, Alon Skaat, Vicktoria Vishnevskia-Dai, Ido Didi Fabian, Oded Sagiv and 3 more

Abstract readComparative Study
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gabriel Katz *Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Ofira Zloto *Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel. ozloto@gmail.com.ORCID http://orcid.org/0000-0002-3548-424X
Avner HostovskyFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Ruth Huna-BaronFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Iris Ben-Bassat MizrachiFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Zvia BurganskyFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Alon SkaatFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Vicktoria Vishnevskia-DaiFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Ido Didi FabianFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID http://orcid.org/0000-0002-0846-5131
Oded SagivFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID http://orcid.org/0000-0003-0563-278X
Ayelet PrielFaculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Benjamin S GlicksbergThe Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-4515-8090
Eyal KlangThe Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the abilities of ChatGPT in writing scientific ophthalmology introductions and to compare those abilities to experienced ophthalmologists.

methodsOpenAI web interface was utilized to interact with and prompt ChatGPT 4 for generating the introductions for the selected papers. Consequently, each paper had two introductions-one drafted by ChatGPT and the other by the original author. Ten ophthalmology specialists with a minimal experience of more than 15 years, each representing distinct subspecialties-retina, neuro-ophthalmology, oculoplastic, glaucoma, and ocular oncology were provided with the two sets of introductions without revealing the origin (ChatGPT or human author) and were tasked to evaluate the introductions.

resultsFor each type of introduction, out of 45 instances, specialists correctly identified the source 26 times (57.7%) and erred 19 times (42.2%). The misclassification rates for introductions were 25% for experts evaluating introductions from their own subspecialty while to 44.4% for experts assessed introductions outside their subspecialty domain. In the comparative evaluation of introductions written by ChatGPT and human authors, no significant difference was identified across the assessed metrics (language, data arrangement, factual accuracy, originality, data Currency). The misclassification rate (the frequency at which reviewers incorrectly identified the authorship) was highest in Oculoplastic (66.7%) and lowest in Retina (11.1%).

conclusionsChatGPT represents a significant advancement in facilitating the creation of original scientific papers in ophthalmology. The introductions generated by ChatGPT showed no statistically significant difference compared to those written by experts in terms of language, data organization, factual accuracy, originality, and the currency of information. In addition, nearly half of them being indistinguishable from the originals. Future research endeavours should explore ChatGPT-4's utility in composing other sections of research papers and delve into the associated ethical considerations.

Indexed as

OphthalmologistsOphthalmologyWritingGenerative Artificial IntelligenceHumans

Identifiers

PMID40169887
PMCPMC12209441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.