Evidence map›Paper›PMID 40169867›Full record

ArticleScientific reports2025

Treatment adherence and its association with family support among pulmonary tuberculosis patients in Jinja, Eastern Uganda.

Businge Alinaitwe, Nilufar Jivraj Shariff, Bindu Madhavi Boddupalli

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Businge AlinaitweRegional Cancer Center, Uganda Cancer Institute, Gulu, Uganda. busingebruceali@gmail.com.
Nilufar Jivraj ShariffSchool of Nursing, Mount Kenya University, Thika, Kenya.
Bindu Madhavi BoddupalliSchool of Pharmacy, Mount Kenya University, Thika, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is a major cause of morbidity globally. Regardless of the efforts to combat the disease, poor treatment adherence has resulted in treatment failure. As such, there is increased community transmission of TB, resulting in a persistently high burden of disease. In this baseline cross-sectional study, the aim was to determine the level of TB treatment adherence and the effect of family support on adherence. Adherence was assessed using a 6-item Medication Adherence Rating Scale (MARS). A total of 147 TB patients were enrolled. Two in three (65.3%, 95% CI 57.6-73.0) of the patients had a high level of adherence. Forms of actual family support, including medication reminders, encouragement, and emotional support, were significantly associated with adherence (p < 0.05). Having no caregivers and missing refill appointments were associated with poor average adherence scores (p < 0.0001). The level of perceived family support moderated the effect of actual family support on adherence (p < 0.05). The findings underscore the significance of both tangible and perceived family support in improving TB treatment adherence. There is a high need to integrate the family support dimensions into TB care. Patients' perceptions regarding family support should inform the design and implementation of adherence-promoting interventions.

Indexed as

Antitubercular AgentsFamilyMedication AdherenceSocial SupportTuberculosis, PulmonaryAdolescentAdultCross-Sectional StudiesFamily SupportFemaleHumansMaleMiddle AgedTreatment Adherence and ComplianceUgandaYoung AdultAntitubercular AgentsAdherence levelFamily caregiversFamily supportMARSPulmonary tuberculosisTB treatment

Identifiers

PMID40169867
PMCPMC11961641

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.