Evidence map›Paper›PMID 40169736›Full record

ArticleScientific reports2025

Tracking WNV transmission with a combined dog and wild boar surveillance system.

Cora M Holicki, Ute Ziegler, Wolfgang Gaede, Kerstin Albrecht, Jana Hänske, Jörg Walraph, Balal Sadeghi, Martin H Groschup, Martin Eiden

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. West Nile virus unmasked: from gene variability to future challenges.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cora M HolickiInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany. c.holicki@erasmusmc.nl.
Ute ZieglerInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Wolfgang GaedeDepartment of Veterinary Medicine, State Office for Consumer Protection Saxony-Anhalt, Haferbreiter Weg 132, 39576, Stendal, Germany.
Kerstin AlbrechtDepartment of Veterinary Medicine, State Office for Consumer Protection Saxony-Anhalt, Haferbreiter Weg 132, 39576, Stendal, Germany.
Jana HänskeDepartment of Veterinary Medicine, Saxon State Laboratory of Health and Veterinary Affairs, Jägerstraße 8/10, 01099, Dresden, Germany.
Jörg WalraphDepartment of Veterinary Medicine, Saxon State Laboratory of Health and Veterinary Affairs, Zschopauer Straße 87, 09111, Chemnitz, Germany.
Balal SadeghiInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Martin H GroschupInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Martin EidenInstitute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany. Martin.Eiden@fli.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

West Nile virus (WNV) is a mosquito-borne flavivirus mainly circulating in eastern Germany, causing annually reoccurring epizootics in the avifauna as well as sporadic infections in humans and horses. WNV is closely-related to Usutu virus (USUV) and tick-borne encephalitis virus (TBEV) and co-infections thereof are becoming more frequent. To not solely be dependent on the monitoring of wild birds and horses the availability of alternative sentinel species is advantageous. The study examined the seroprevalence of WNV antibodies (Abs) in eastern Germany in readily available species: dogs, wild boars, sheep, and goats. An NS1-ELISA was implemented to ease future differentiation of cross-reacting flavivirus Abs with a sensitivity of 92.3 and 90.9% for dog and wild boar sera, respectively. Flavivirus seroprevalences were the highest in wild boars with 42.03%, followed by dogs with 7.86%, and small ruminants with 1.57%. In the wild boars and dogs, WNV Abs were most frequent (17.64 and 3.90%, respectively) while seroprevalences in small ruminants and of USUV were lower. The NS1-ELISA is cost-efficient and reliable in monitoring WNV Abs in dogs as well as wild boars and the combined testing thereof could be ideal in detecting semi-urban transmission events prior to wildlife-human spill overs.

Indexed as

Sus scrofaWest Nile FeverWest Nile virusAnimalsAntibodies, ViralDogsEnzyme-Linked Immunosorbent AssayGermanySeroepidemiologic StudiesSwineAntibodies, Viral

Identifiers

PMID40169736
PMCPMC11962116

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.