Evidence map›Paper›PMID 40169725›Full record

ArticleScientific reports2025

Study of the effect of dryness and storage on Ceratonia siliqua L. stem extracts and evaluation of their insecticidal activity.

Esraa A Elhawary, Mohammed E Gad, Maysa M Hegazy, Reham M Mostafa, Hattan S Gattan, Mohammed H Alruhaili, Abdelfattah M Selim, Abadi M Mashlawi, Abeer Mousa Alkhaibari, Saeed M Alasmari and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Sustainable MnOPharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Esraa A ElhawaryDepartment of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, 11566, Egypt. esraa.elhawary@pharma.asu.edu.eg.
Mohammed E GadDepartment of Zoology and Entomology, Faculty of Science, Al-Azhar University, Nasr City, 11884, Cairo, Egypt.
Maysa M HegazyBiology Department, Faculty of Science, Jazan University, Jazan, Saudi Arabia.
Reham M MostafaBotany and Microbiology Department, Faculty of Science, Benha University, Benha, 13518, Egypt.
Hattan S GattanDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed H AlruhailiDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King AbdulAziz University, Jeddah, Saudi Arabia.
Abdelfattah M SelimDepartment of Animal Medicine (Infectious Diseases), College of Veterinary Medicine, Benha University, Toukh, 13736, Egypt. Abdelfattah.selim@fvtm.bu.edu.eg.
Abadi M MashlawiDepartment of Biology, College of Science, Jazan University, 45142, Jazan, Kingdom of Saudi Arabia.
Abeer Mousa AlkhaibariDepartment of Biology, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia.
Saeed M AlasmariDepartment of Biology, Faculty of Science and Arts, Najran University, 1988, Najran, Saudi Arabia.
Mohamed M BazDepartment of Biology, Faculty of Education and Arts, Sohar University, Sohar, 311, Oman. Mohamed.albaz@fsc.bu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vector-borne diseases continue to transmit many dangerous pathogens to humans. After decades of continuous use of insecticides, many types of vectors have shown the ability to build resistance to them. This has necessitated the development of more efficient and environmentally friendly alternatives in the form of bioinsecticides. Plants contain a wide range of phytochemicals with specific targeting, rapid biodegradability, environmental sustainability and a variety of medicinal properties, making them a valuable source of biologicals. Moreover, this has led to the development of highly effective new drugs. This study aimed to identify the active ingredients in Ceratonia siliqua L., gathered from two consecutive fruiting seasons which were then divided into C. siliqua fresh (CSF), dry (CSd), and old (stored) stem (CSO) extracts Ceratonia siliqua. Metabolomics profiling was performed using UPLC/MS and multivariate data analysis. The UPLC/MS study resulted in the tentative identification of 54 secondary metabolites. These compounds included flavonoids, phenolic acids, withanolides, terpenoids, phenylpropanoids, etc. CSd showed the highest number of identified components followed by CSO and CSF. The % identification was nearly equal in the negative ion mode for the three extracts while for the positive ion mode it followed the order of CSF > CSd > CSO. After several exposure periods, the plant methanol extracts in this research showed significant insecticidal activity against mosquito larvae, Cx. pipiens, and housefly larvae M. domestica. (CSd) demonstrated the highest insecticidal activity (100 MO%) against Cx. pipiens (LC

Indexed as

InsecticidesPlant ExtractsPlant StemsAnimalsLarvaInsecticidesPlant ExtractsBiocontrolCeratonia siliquaCulexLarvicidal activityMuscaSolanaceae

Identifiers

PMID40169725
PMCPMC11961609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.