Evidence map›Paper›PMID 40169627›Full record

ArticleScientific reports2025

Structural changes in vortex vein ampullae in eyes with pachychoroid-spectrum disorder.

Ryoh Funatsu, Hiroto Terasaki, Shozo Sonoda, Naohisa Mihara, Mariko Hirokawa, Yasushi Tanabe, Hideki Shiihara, Taiji Sakamoto

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hormonal factors in the pathophysiology of central serous chorioretinopathy - a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryoh FunatsuDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima, Kagoshima, Japan.
Hiroto TerasakiDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima, Kagoshima, Japan. teracchi@m2.kufm.kagoshima-u.ac.jp.
Shozo SonodaDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima, Kagoshima, Japan.
Naohisa MiharaDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima, Kagoshima, Japan.
Mariko HirokawaHealthcare Business Unit, Nikon Corporation, Tokyo, Japan.
Yasushi TanabeHealthcare Business Unit, Nikon Corporation, Tokyo, Japan.
Hideki ShiiharaDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima, Kagoshima, Japan.
Taiji SakamotoDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima, Kagoshima, Japan.

Funding

Japan Society for the Promotion of Science 24K12746Japan Society for the Promotion of Science 24KJ1842
6 · The paper itself

Abstract

The purpose of this study is to identify the characteristics of vortex vein ampullae in pachychoroid-spectrum disorders. This case-control study evaluated vortex vein ampullae using Optos Silverstone, an imaging device combining ultra-widefield scanning laser fundus imaging with swept-source optical coherence tomography. Consecutive patients with pachychoroid-spectrum disorders and controls who visited Kagoshima university hospital between January 2022 and December 2023 and underwent vortex vein ampullae evaluations. We compared morphological parameters of supratemporal and infratemporal vortex vein ampullae between eyes with pachychoroid-spectrum disorders and control subjects. We included 40 patients (46 eyes) with pachychoroid-spectrum disorders, and 14 healthy controls (15 eyes). We observed no significant differences in any supratemporal vortex vein ampullae morphological parameters (P ≥ 0.487 for all comparisons). In infratemporal vortex vein ampullae, eyes with pachychoroid-spectrum disorders showed significantly larger mean luminal volume (6.9 × 10

Indexed as

ChoroidChoroid DiseasesRetinal VeinAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedTomography, Optical Coherence

Identifiers

PMID40169627
PMCPMC11961724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.