ArticleNature communications2025
Second coordination sphere regulates nanozyme inhibition to assist early drug discovery.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed.
- Ru-N coordination hydrogen-bonded organic frameworks with enhanced peroxidase-like activity for colorimetric determination of gastric cancer-related salivary D-amino acids.Mikrochimica acta · 2026Article
- Deciphering the Catalytic Mechanism of Oxidoreductase-Like Nanozymes Along the Reaction Pathway: Activity, Specificity and Sustainability.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Electron Delocalization Induced by 3d-4f Orbital Hybridization of Co─Ce Atom Pairs Toward Enhanced Electromagnetic Wave Attenuation and Antibacterial Performance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cobalt(II)-Mediated Fenton-like Reactions: Effects of Second-Sphere HInorganic chemistry · 2026Article
- Endocrine nanozymology: Nanozyme applications in diabetes, obesity, and hormonal disorders.Theranostics · 2026Review
- Bi-Doped Pd Aerogels with Tensile-Strain-Induced Cascade Orbital Hybridization Boost HResearch (Washington, D.C.) · 2026Article
- Second coordination sphere regulates nanozyme inhibition to assist early drug discovery.Nature communications · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Early drug discovery is a time- and cost-consuming task requiring enzymes. Although nanozymes with metal sites akin to metallocofactors display similar activities, the lack of proximal amino acids hinders them from more adequately mimicking enzymes for drug discovery purposes. Hence, the rational design of the nanozyme second coordination sphere is desirable yet remains challenging. Herein, we report a nanozyme featuring atomically dispersed Cu-N
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Registered trials
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