Evidence map›Paper›PMID 40169508›Full record

ArticleUpdates in surgery2025

Intraoperative nerve monitoring in thyroid and parathyroid surgery: a decade of Italian practice.

R Melcarne, G Docimo, P S L Aiello, S Andreani, N Avenia, G Basili, C Bellotti, D Bettini, M Biffoni, M Bononi and 36 more

Abstract read
In one paragraph

Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors.

R MelcarneDepartment of Translational and Precision Medicine, Sapienza University of Rome, Viale del Policlinico, 155, 00161, Rome, Italy. rossella.melcarne@uniroma1.it.ORCID http://orcid.org/0000-0002-2820-7607
G DocimoDivision of Thyroid Surgery, University of Campania "L. Vanvitelli", Naples, Italy.
P S L AielloEndocrine Surgery Unit, Department of General Oncology and Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy.
S AndreaniEndocrine Surgery Unit, Department of General Oncology and Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy.
N AveniaGeneral and Endocrine Surgery Unit, S. Maria University Hospital, University of Perugia, 05100, Terni, Italy.
G BasiliGeneral Surgery Department, Endocrine Surgery Unit, Azienda USL Toscana Nord-Ovest, Pontedera, Italy.
C BellottiDipartimento di Scienze Medico-Chirurgiche e Medicina Traslazionale, Università Sapienza di Roma, Rome, Italy.
D BettiniEndocrine Surgery Unit, "Morgagni-Pierantoni" Hospital, Forli, Italy.
M BiffoniUOSD Endocrine Surgery - Department of General and Speciality Surgery, Sapienza University, 00185, Rome, Italy.
M BononiDepartment of Surgery, Sapienza University, Rome, Italy.
A BoveDepartment of Medicine, Dentistry and Biotechnology, University "G. D'Annunzio", Chieti, Italy.
P G CalòDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
A CasarilEndocrine Surgery Unit, Pederzoli Hospital, Peschiera del Garda, Verona, Italy.
G CavallaroDepartment of Surgery, Sapienza University, Rome, Italy.
M G ChiofaloPathology Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy.
F ConsortiDepartment of Surgery, Sapienza University, Rome, Italy.
C De CreaUOC Chirurgia Endocrina, Ospedale Isola Tiberina, Gemelli Isola, Rome, Italy.
L De PasqualeThyroid Unit, Department of Health Sciences, Santi Paolo e Carlo Hospital, Università degli Studi di Milano, Milan, Italy.
P Del RioUnit of General Surgery, Department of Medicine and Surgery, University of Parma, Parma, Italy.
C DobrinjaGeneral Surgery Unit, Department of Medicine, Surgery and Health Sciences, University of Trieste, Cattinara University Hospital, Strada di Fiume 447, 34149, Trieste, Italy.
L GiacomelliUOSD Endocrine Surgery - Department of General and Speciality Surgery, Sapienza University, 00185, Rome, Italy.
G GraceffaDepartment of Surgical Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
A GurradoDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University Medical School of Bari, 70124, Bari, Italy.
M IacoboneEndocrine Surgery Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padua, Italy.
N InnaroUnit of Endocrine Surgery, AOU "Dulbecco", University "Magna Graecia" of Catanzaro, 88100, Catanzaro, Italy.
E LeopaldiSurgery Department, IGEA Private Hospital, Milan, Italy.
G Lupone"A. Cardarelli" Hospital, Naples, Italy.
G MaterazziEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
M MinutoDepartment of Surgical Sciences and Integrated Diagnostics, University of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
B MullinerisUnit of General Surgery, Emergency and New Technologies, Modena Hospital, 41126, Modena, Italy.
N PalestiniHumanitas - Clinica Fornaca di Sessant Private Hospital, Turin, Italy.
R PanconesiEndocrinology Unit, Careggi Hospital and University of Florence, Florence, Italy.
I PaunaEndocrine Surgery Unit, Department of General Oncology and Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy.
A PezzollaDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University Medical School of Bari, 70124, Bari, Italy.
I P PisanoIstituto di Patologia Chirurgica AOU, Sassari, Italy.
P PrinciUOC Centro Multifunzionale di Chirurgia Endocrina, Ospedale Cristo Re, Rome, Italy.
F QuaglinoDepartment of General Surgery, Maria Vittoria Hospital, ASL City of Turin, Turin, Italy.
M RaffaelliCentro di Ricerca in Chirurgia delle Ghiandole Endocrine e dell'Obesità, Università Cattolica del Sacro Cuore, Rome, Italy.
L RosatoDepartment of Surgery-ASL TO4, Ivrea Hospital, 10015, Ivrea, Italy.
P V SartoriGeneral Surgical Department, ASST Brianza-Pio XI Hospital, 20832, Desio, Italy.
G ScerrinoDepartment of Surgical Oncological and Oral Sciences, University of Palermo, 90127, Palermo, Italy.
F ScolariEndocrine Surgery Unit, Department of General Oncology and Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy.
M TestiniDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University Medical School of Bari, 70124, Bari, Italy.
E TrainiEndocrine Surgery Unity, Ospedale San Carlo di Nancy GVM, Via Aurelia, 275, 00165, Rome, Italy.
SIUEC IONM Collaborative Group
M BoniardiEndocrine Surgery Unit, Department of General Oncology and Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, 20162, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraoperative nerve monitoring (IONM) has been recognized as a useful adjunct into the field of thyroid and parathyroid surgery, aiding in the accurate identification and preservation of the recurrent laryngeal nerve (RLN), consequently reducing the probability of nerve injury and promoting surgical safety. This investigation seeks to amplify the findings of a similar nationwide survey performed in 2014 by offering an updated assessment of IONM practices among Italian surgical institutions, reflecting a decade of advancements and transformations in clinical approaches. A comprehensive nationwide survey was implemented targeting Italian endocrine surgeons to assess the prevalence, utilization patterns, attitudes and perceptions surrounding IONM in the context of thyroid and parathyroid surgical procedures. Structured questionnaires were administered to seventy endocrine surgery centers, and the resulting data were evaluated employing both quantitative and qualitative analysis methods. The survey disclosed that 67.14% of the participants confirmed the routine deployment of IONM across all cervical surgical procedures, particularly in high-risk contexts. Relative to the findings from 2014, a marked rise in the implementation of IONM has been recorded; however, variability persists, especially between continuous and intermittent monitoring strategies. Surgeons recognized improved surgical safety, decreased complication frequencies, and educational advantages as significant key drivers for the incorporation of IONM. Nonetheless, issues, such as false-positive and false-negative results, along with the lack of standardized protocols, remain barriers to its uniform application. During the past ten years, IONM has been thoroughly adopted by Italian endocrine surgeons as a result of its critical contribution to the improvement of surgical outcomes and the provision of educational resources. However, the results highlight the imperative for further standardization of protocols, the advancement of training programs, and the resolution of reimbursement obstacles to ensure equitable and consistent application of IONM across Italian centers, ultimately optimizing patient care.

Indexed as

Monitoring, IntraoperativeParathyroidectomyParathyroid GlandsPractice Patterns, Physicians'Recurrent Laryngeal NerveRecurrent Laryngeal Nerve InjuriesThyroidectomyThyroid GlandHumansItalySurveys and QuestionnairesClinical outcomesNerve protectionParathyroid surgeryRecurrent laryngeal nerveSurgical safetyThyroidectomy

Identifiers

PMID40169508
PMCPMC12420727

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.