Evidence map›Paper›PMID 40169464›Full record

ArticleAnnals of biomedical engineering2025

Vascular Flow Phantom of A Cohort-Based Averaged Abdominal Aortic Aneurysm: Design, Fabrication and Characterization.

H Mirgolbabaee, J R Nagel, J Plomp, A Ghanbarzadeh-Dagheyan, J A Simmering, M Versluis, M M P J Reijnen, E Groot Jebbink

Abstract read
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In one paragraph

Article in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Development and Characteristics of a Dual-Layered Vascular Phantom.Cardiovascular engineering and technology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

H Mirgolbabaee *Multi-Modality Medical Imaging (M3I) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0001-6291-7170
J R Nagel *Multi-Modality Medical Imaging (M3I) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0002-4816-9214
J PlompMulti-Modality Medical Imaging (M3I) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0009-0008-1671-5162
A Ghanbarzadeh-DagheyanBiomedical Photonic Imaging (BMPI) Group, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0003-3640-2821
J A SimmeringMulti-Modality Medical Imaging (M3I) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0002-6178-1635
M VersluisPhysics of Fluids (PoF) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0002-2296-1860
M M P J ReijnenMulti-Modality Medical Imaging (M3I) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands.ORCID http://orcid.org/0000-0002-5021-1768
E Groot JebbinkMulti-Modality Medical Imaging (M3I) Group, Technical Medical Centre, University of Twente, Enschede, The Netherlands. e.grootjebbink@utwente.nl.ORCID http://orcid.org/0000-0001-7041-8603

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVascular flow phantoms are an invaluable tool for in vitro and in silico studies, but their design and fabrication processes are often not reported. In this study, a framework is introduced to design and fabricate 3D printable high-fidelity cohort-based averaged abdominal aortic aneurysm (AAA) phantoms.

methodsAAA geometries of 50 patients were segmented from preoperative computed tomography angiography scans. The segmented geometries and center lumen lines (CLL) were used in an in-house developed algorithm to average the CLL coordinates and corresponding diameters over the entire cohort. The reconstructed averaged anatomy was 3D printed as a thin-walled flow phantom with Formlabs Flexible 80A resin. The acoustic properties of the resin were characterized and the feasibility of flow field quantification inside the phantom with ultrasound particle imaging velocimetry (echoPIV) was investigated.

resultsComparison between patient-specific models generated by our method and their corresponding reference segmentations, for ten patients, showed a mean Sørensen-Dice similarity coefficient of 0.916 ± 0.21 and the largest distances (5-10% of the lumen diameter) were found at the aneurysmal sac. The Flexible 80A resin had an average speed of sound of 1785 m/s, attenuation of 7.8 dB/mm and density of 1130 kg/m

conclusionThe reported framework was used to make an averaged, cohort-based AAA model, which showed a good match with its reference model. A 3D printed, thin-walled phantom was made based on this model and the feasibility of flow field quantification inside the phantom was shown.

Indexed as

Aortic Aneurysm, AbdominalModels, CardiovascularPhantoms, ImagingAgedAged, 80 and overCohort StudiesComputed Tomography AngiographyFemaleHumansMaleMiddle AgedPrinting, Three-DimensionalAbdominal aortic aneurysmAcoustic characterizationAveraged anatomyParticle image velocimetryPhantom fabricationPhantom modeling

Identifiers

PMID40169464
PMCPMC12075298

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.