Evidence map›Paper›PMID 40169378›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2025

Inequalities in Access to Specialist Allergy Services in the United Kingdom: A Report From the BSACI Registry for Immunotherapy (BRIT).

Mich Erlewyn-Lajeunesse, Luciano Perfetti Villa, Shifa Shaikh, Maria Smith, Vasiliki Balodima, Sarah Baker, Tom Dawson, Pamela Ewan, Sujoy Khan, Deborah Marriage and 6 more

Abstract read
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Adrenaline Auto-Injector Prescribing in Primary Care in England: An Analysis of Non-Standard Dosing.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  4. Identifying and Prioritising BSACI Service Standards for Paediatric Allergy in the United Kingdom.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mich Erlewyn-LajeunesseUniversity of Southampton and Southampton Children's Hospital, Southampton, UK.ORCID https://orcid.org/0000-0003-1982-1397
Luciano Perfetti VillaDepartment of Social Statistics and Demography, University of Southampton, Southampton, UK.
Shifa ShaikhBritish Society for Allergy and Clinical Immunology, London, UK.
Maria SmithBritish Society for Allergy and Clinical Immunology, London, UK.
Vasiliki BalodimaUniversity Hospital Southampton, Southampton, UK.
Sarah BakerAnaphylaxis UK, Farnborough, UK.
Tom DawsonWorcestershire Acute Hospitals NHS Trust, Worcester, UK.
Pamela EwanCambridge University Hospitals NHS Foundation Trust and University of Cambridge Clinical School, Cambridge, UK.
Sujoy KhanCastle Hill Hospital, Cottingham, UK.
Deborah MarriageUniversity Hospitals Bristol and Weston, Bristol, UK.
Louise MichaelisGreat Northern Children's Hospital, UK.ORCID https://orcid.org/0000-0001-8229-154X
Leyla Pur OzygitGlenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK.
Anna Thursby-PelhamUniversity Hospital Bristol and Weston NHS Trust, Bristol, UK.
Amena WarnerAllergy UK, UK.
Olga MaslovskayaDepartment of Social Statistics and Demography, University of Southampton, Southampton, UK.
BRIT Practitioners Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is an unmet need for specialist allergy treatment in the United Kingdom. Allergen immunotherapy and treatment with omalizumab for chronic spontaneous urticaria (CSU) are key markers for these services. The British Society for Allergy and Clinical Immunology (BSACI) Registry for Immunotherapy (BRIT) is a national project to record the real-world effectiveness, safety and access to treatment for aero-allergen, venom and peanut immunotherapy as well as omalizumab for CSU.

methodsWe described participant demographics, the index of multiple deprivation (IMD) and access to treatment from the registry launch. Data for 1835 participants were available for analysis from 63 centres enrolled between 1st October 2018 and 24th August 2023.

results96.5% (1771/1835) were living in England, with only 3.5% (64) being from the devolved nations. 14.4% (251/1748) were in the most affluent IMD decile compared to 4.5% (78/1748) in the most deprived IMD decile. White participants were 1.74 times more likely to be referred directly from primary care compared to people of Asian, black, mixed or other minority ethnic groups. Instead, these groups were referred more frequently from secondary or tertiary hospital services. The median distance travelled from home to the treatment centre was 15.2 miles, with evidence of clustering around specialist centres.

conclusionsWe have described disparities and unwarranted variation in the provision of treatment around the UK. The data suggest that there is limited access to immunotherapy in the devolved nations. Access is also reduced by socioeconomic deprivation. White participants were more likely to receive a direct referral from primary care than those from other ethnic groups whose referral pathways were more complex. Registry data are limited by participant enrolment and may have selection bias. Nevertheless, BRIT has highlighted inequity in access to specialist allergy services in the UK.

Indexed as

Desensitization, ImmunologicHealthcare DisparitiesHealth Services AccessibilityHypersensitivityAdolescentAdultAgedChildChild, PreschoolFemaleHumansMaleMiddle AgedOmalizumabRegistriesSocioeconomic FactorsOmalizumaballergenallergybasic immunologybiologicsclinical immunologyfood allergyimmunotherapyimmunotherapy and tolerance inductionvenom and insect allergy

Identifiers

PMID40169378
PMCPMC12127059

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.