Evidence map›Paper›PMID 40168585›Full record

ArticleAIDS care2025

Human-centered design of an adapted differentiated service delivery model for pregnant and postpartum women living with HIV in Kenya.

John Humphrey, Bett Kipchumba, James G Carlucci, Roselyne Midiwo, Edwin Were, Alan McGuire, Julia Songok, Winstone Nyandiko, Gregory Zimet, Kara Wools-Kaloustian and 1 more

Abstract read
In one paragraph

Article in AIDS care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John HumphreyDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Bett KipchumbaDepartment of Reproductive Health, Moi University School of Medicine, Eldoret, Kenya.
James G CarlucciDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Roselyne MidiwoAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Edwin WereDepartment of Reproductive Health, Moi University School of Medicine, Eldoret, Kenya.
Alan McGuireDepartment of Psychology, Indiana University-Purdue University, Indianapolis, IN, USA.
Julia SongokDepartment of Child Health and Paediatrics, Moi University School of Medicine, Eldoret, Kenya.
Winstone NyandikoDepartment of Child Health and Paediatrics, Moi University School of Medicine, Eldoret, Kenya.
Gregory ZimetDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Kara Wools-KaloustianDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Violet NaanyuDepartment of Sociology, Psychology and Anthropology, Moi University School of Arts and Social Science, Eldoret, Kenya.

Funding

Developing an enhanced Mentor Mother strategy to improve prevention of mother-to-child transmission of HIV (PMTCT) outcomesK23HD109056 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI JAMES G CARLUCCI · 2022 to 2026
$772k
Adaptation, execution, and evaluation of a differentiated service delivery model for PMTCTK23HD105495 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI HUMPHREY, JOHN M · 2021 to 2025
$722k
NICHD NIH HHS K23 HD105495NICHD NIH HHS K23 HD109056
6 · The paper itself

Abstract

Differentiated service delivery (DSD) models for pregnant and postpartum women living with HIV (WLH) are lacking despite guidelines recommending DSD for this population. We used human-centered design (HCD) to develop a DSD model for pregnant and postpartum WLH at the Academic Model Providing Access to Healthcare (AMPATH) in Kenya. We conducted co-creation workshops with 11 postpartum women, 9 male partners and 9 providers from three AMPATH-affiliated facilities to develop a DSD model, refined by program/county health officials. The workshops used WHO building blocks for DSD to determine eligibility criteria and strategies for clinical encounters, antiretroviral therapy (ART) distribution, and psychosocial support. We used nominal group techniques and thematic analyses to identify DSD attributes, themes and preference heterogeneity. Workshops yielded a facility-based DSD model with these attributes: eligibility criteria including age ≥18 years, not primigravida, retention in care, viral load <50 copies/mL, no active maternal/child comorbidities; monthly clinical encounters during pregnancy and 6 months postpartum, then every 2-3 months aligned with immunization/HIV testing schedules; flexible ART refills every 1-6 months; psychosocial counseling by mentor mothers as needed. This model was acceptable to stakeholders with perceived feasibility/scalability. Engaging end-users through HCD generated a person-centered DSD model for integrated MCH clinics in Kenya.

Indexed as

Delivery of Health CareHIV InfectionsPregnancy Complications, InfectiousAdultAnti-HIV AgentsFemaleHumansKenyaMalePatient-Centered CarePostnatal CarePostpartum PeriodPregnancyYoung AdultAnti-HIV AgentsHIV-exposed infantimplementationretentionSDG 3: Good health and well-beingVertical transmissionviremia

Identifiers

PMID40168585
PMCPMC12353083

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.