Evidence map›Paper›PMID 40168179›Full record

ArticleACS applied materials & interfaces2025

Design and Characterization of DNA-Driven Condensates: Regulating Topology, Mechanical Properties, and Immunorecognition.

Elizabeth Skelly, Christina J Bayard, Joel Jarusek, Benjamin Clark, Laura P Rebolledo, Yasmine Radwan, Phong Nguyen, Melanie Andrade-Muñoz, Thomas A Deaton, Alexander Lushnikov and 4 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elizabeth SkellyChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Christina J BayardDepartment of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States.ORCID 0009-0002-5344-3713
Joel JarusekDepartment of Physics, University of Nebraska Omaha, Omaha, Nebraska 68182, United States.ORCID 0000-0002-9088-8538
Benjamin ClarkDepartment of Physics, North Carolina State University, Raleigh, North Carolina 27695-8202, United States.
Laura P RebolledoChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Yasmine RadwanChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Phong NguyenChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Melanie Andrade-MuñozChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.
Thomas A DeatonDepartment of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States.
Alexander LushnikovDepartment of Physics, University of Nebraska Omaha, Omaha, Nebraska 68182, United States.
Sharonda J LeBlancDepartment of Physics, North Carolina State University, Raleigh, North Carolina 27695-8202, United States.
Alexey V KrasnoslobodtsevDepartment of Physics, University of Nebraska Omaha, Omaha, Nebraska 68182, United States.
Yaroslava G YinglingDepartment of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27695, United States.ORCID 0000-0002-8557-9992
Kirill A AfoninChemistry and Nanoscale Science Program, Department of Chemistry, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, United States.ORCID 0000-0002-6917-3183

Funding

SMART NANPs: new molecular platform for communication with human immune system and modulation of therapeutic responsesR35GM139587 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI AFONIN, KIRILL A · 2021 to 2025
$1.8M
NIGMS NIH HHS R35 GM139587
6 · The paper itself

Abstract

Cells maintain spatiotemporal control over biochemical processes through the formation and dissolution of biomolecular condensates, dynamic membraneless organelles formed via liquid-liquid phase separation. Composed primarily of proteins and nucleic acids, these condensates regulate key cellular functions, and their properties are influenced by the concentration and type of molecules involved. The structural versatility challenges the

Indexed as

Biomolecular CondensatesDNAHumansNanotechnologyOligonucleotidesDNAOligonucleotidescGAS-STINGdissipative particle dynamicsmicrorheologynucleic acid condensatesquantum dotsstimuli responsiveness

Identifiers

PMID40168179
PMCPMC12012714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.