Evidence map›Paper›PMID 40168163›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Using Simulation to Optimize the Design of Adaptive Clinical Trials.

Cal H Robinson, Rulan S Parekh, Brian H Cuthbertson, Eddy Fan, Yongdong Ouyang, Anna Heath

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cal H RobinsonDivision of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-2223-0646
Rulan S ParekhDivision of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Brian H CuthbertsonInterdepartmental Division of Critical Care Medicine, The University of Toronto, Toronto, Ontario, Canada.
Eddy FanInterdepartmental Division of Critical Care Medicine, The University of Toronto, Toronto, Ontario, Canada.
Yongdong OuyangChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Anna HeathChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0002-7263-4251

Funding

Cure Glomerulonephropathy Consortium, Sickkids Research Institute, Canadian Institutes of Health Research, Kidney Foundation of Canada, Women's College Research Institute
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40168163
PMCPMC11975235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.