ArticleLiver international : official journal of the International Association for the Study of the Liver2025
Incidence and Predictors of Complications Following Percutaneous Liver Biopsy: A Large Italian Multicentre Study.
Article in Liver international : official journal of the International Association for the Study of the Liver, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Randomized trial of biopsy needle sandblasting in coaxial core-needle liver biopsy: no significant improvement in ultrasound visibility, pain, or tissue yield.Abdominal radiology (New York) · 2026Trial
- Toward a future role for liver biopsy in HCC: literature evidence and survey-based perspectives from Korean experts.Journal of liver cancer · 2026Article
- Observational
- Associations between diffusion-weighted imaging and immunohistochemical features in hepatocellular carcinoma: a preliminary analysis of tumor-infiltrating lymphocytes and microvessel density expression.Clinical and experimental hepatology · 2025Article
- Hepatotoxicity in Cancer Immunotherapy: Diagnosis, Management, and Future Perspectives.Cancers · 2024Review
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Authors and funding
25 authors.
Funding
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Abstract
BACKGROUND AND
aimsManagement of ultrasound (US)-guided percutaneous liver biopsy (PLB) lacks standardisation. Despite the low risk of major complications (< 1%), repeated blood counts and up to 4 h of in-hospital observation are typically recommended. We aimed to assess complication rates and predictors in a large cohort of patients undergoing US-PLB across three Italian tertiary centres. We included all patients undergoing US-PLB from January 2018 to December 2023. We collected clinical, biochemical and procedural features (needle type, insertions number, observation time and antiplatelet/anticoagulant regimens). Safety was assessed by the incidence of pain and major complications, including vasovagal reaction, bleeding, pneumothorax, shock, hospitalisation and death. APPROACH AND
resultsAmong 1838 patients (mean age 55.1 years, 46.1% females, mean BMI 25.1 kg/m
conclusionsMajor complications following US-PLB are few and strongly associated with early post-procedural pain. In the absence of pain within the first hour, extended monitoring may be unnecessary, allowing for earlier patient discharge.
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