Evidence map›Paper›PMID 40168116›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

No compelling evidence of sex differences in brain maturation during COVID-19 lockdowns when the sexes are compared statistically.

Andrew W Brown, Simon Chung, Timothy Koscik, Colby J Vorland, Donna L Maney

Abstract readLetter
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Reply to Brown et al.: Significant sex differences in accelerated cortical thinning associated with the COVID-19 lockdowns.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew W BrownDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR 72205.ORCID 0000-0002-1758-8205
Simon ChungDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR 72205.
Timothy KoscikArkansas Children's Research Institute, Little Rock, AR 72202.
Colby J VorlandDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN 47403.ORCID 0000-0003-4225-372X
Donna L ManeyDepartment of Psychology, Emory University, Atlanta, GA 30322.

Funding

SCISIPBIO: Maximizing rigor and reproducibility when considering Sex as a Biological Variable in researchR01GM152543 · NIGMS · EMORY UNIVERSITY · PI DONNA L MANEY, Colby Vorland · 2023 to 2026
$734k
Removing Barriers to Better Data Practices through Capacity, Opportunity, and MotivationR25GM141507 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BROWN, ANDREW W · 2021 to 2023
$270k
HHS | National Institutes of Health (NIH) R01GM152543HHS | National Institutes of Health (NIH) R25GM141507National Science Foundation (NSF) 2318478NIGMS NIH HHS R01 GM152543NIGMS NIH HHS R25 GM141507
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40168116
PMCPMC12002345

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.