Evidence map›Paper›PMID 40167951›Full record

ArticleCerebellum (London, England)2025

What are the Key Challenges Faced by Spinocerebellar Degeneration and Multiple System Atrophy Patients in Daily Life?: Insights from a Comprehensive Questionnaire Survey in Japan.

Yuki Kondo, Akiyoshi Matsugi, Kyota Bando, Yutaka Kikuchi, Hiromi Maruyama, Yuta Miyazaki, Takatoshi Hara, Yuji Takahashi, Hidehiro Mizusawa

Abstract read
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In one paragraph

Article in Cerebellum (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuki KondoDepartment of Physical Rehabilitation, National Center of Neurology and Psychiatry, National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira-shi, Tokyo, 187-8551, Japan. kondo.ncnp@gmail.com.
Akiyoshi MatsugiFaculty of Rehabilitation, Shijonawate Gakuen University, 5-11-10, Hojo, Daito-Shi, 574-0011, Osaka, Japan.
Kyota BandoDepartment of Physical Rehabilitation, National Center of Neurology and Psychiatry, National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira-shi, Tokyo, 187-8551, Japan.
Yutaka KikuchiDepartment of Rehabilitation for Intractable Neurological Disorders, Mihara Memorial Hospital, 366, Otamachi, Isesaki-Shi, Gumma, 372-0006, Japan.
Hiromi MaruyamaThe Japanese Society of Ataxia Patients, 2-7-2 Kitaotsuka Toshima-ku, Tokyo, 170-0004, Japan.
Yuta MiyazakiDepartment of Physical Rehabilitation, National Center of Neurology and Psychiatry, National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira-shi, Tokyo, 187-8551, Japan.
Takatoshi HaraDepartment of Physical Rehabilitation, National Center of Neurology and Psychiatry, National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira-shi, Tokyo, 187-8551, Japan.
Yuji TakahashiDepartment of Neurology, National Center of Neurology and Psychiatry, National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira-shi, Tokyo, 187-8551, Japan.
Hidehiro MizusawaDepartment of Neurology, National Center of Neurology and Psychiatry, National Center Hospital, 4-1-1 Ogawa-higashi-cho, Kodaira-shi, Tokyo, 187-8551, Japan.

Funding

Japan Society for the Promotion of Science JP21K17485
6 · The paper itself

Abstract

backgroundPatients with spinocerebellar degeneration (SCD) and multiple system atrophy (MSA) encounter various challenges in daily life due to ataxia and other symptoms. A comprehensive understanding of their diverse needs can improve the effectiveness of rehabilitation interventions.

objectiveThis study aims to identify the daily challenges faced by patients with SCD and MSA in Japan, focusing on differences between ambulatory and non-ambulatory patients.

methodsA postal survey was conducted from March to May 2023, targeting members of the Japanese Society of Ataxia Patients diagnosed with SCD and MSA. The questionnaire assessed respondent demographics and symptoms impacting daily life.

resultsFrom the 283 responses received, 152 were deemed valid for analysis. Non-ambulatory patients reported significantly more difficulties across multiple items in the activities domain. Furthermore, subjective unsteadiness, difficulty speaking, and increased fall risk were identified as having the most significant impact on daily life, regardless of walking ability.

conclusionThese findings highlight the need to adapt rehabilitation approaches for patients with SCD and MSA as their disease progresses, emphasizing comprehensive assessment methods and multidisciplinary care to enhance their quality of life.

Indexed as

Activities of Daily LivingMultiple System AtrophySpinocerebellar DegenerationsAdultAgedFemaleHumansJapanMaleMiddle AgedQuality of LifeSurveys and QuestionnairesDaily life challengesMobility statusMultiple system atrophyPostal surveyRehabilitationSpinocerebellar degeneration

Identifiers

PMID40167951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.