ReviewLa Radiologia medica2025
New insights into imaging of pulmonary metastases from extra-thoracic neoplasms.
Review in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Pulmonary tularemia presenting as bilateral pulmonary nodules during BEP chemotherapy for testicular embryonal carcinoma: A diagnostic challenge.Radiology case reports · 2026Article
- Clinical Relevance of Calcifications in Osteosarcoma Lung Metastases: Correlations Among Radiological Patterns, Histological Subtypes, and Chemotherapy Responses.Clinics and practice · 2026Article
- When a Pulmonary Nodule Mimics Malignancy: Primary Granular Cell Tumor of the Lung.Diagnostics (Basel, Switzerland) · 2026Article
- Complete resection of solitary pulmonary metastases in thyroid cancer: a case series report.Journal of cardiothoracic surgery · 2026Article
- Cavitary pulmonary metastasis from renal pelvic urothelial carcinoma with pathological evidence of bronchiolar obstruction supporting a check-valve mechanism: a case report.Respiratory medicine case reports · 2026Article
- Development of a Glymphatic Pathway-based Rat Model for Cancer Metastasis from Brain to Lung.In vivo (Athens, Greece)Article
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Authors and funding
13 authors.
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Abstract
The lung is one of the most common sites of metastases from extra-thoracic neoplasms. Lung metastases can show heterogeneous imaging appearance, thus mimicking a wide range of lung diseases, from benign lesions to primary lung cancer. The proper interpretation of pulmonary findings is crucial for prognostic assessment and treatment planning, even to avoid unnecessary procedures and patient anxiety. For this purpose, computed tomography (CT) is one of the most used imaging modalities. In the last decades, cancer patients' population has steadily increased and, due to the widespread application of CT for staging and surveillance, the detection of pulmonary nodules has raised, making their characterization and management an urgent and mostly unsolved problem for both radiologists and clinicians. This review will highlight the pathways of dissemination of extra-thoracic tumours to the lungs and the heterogeneous CT imaging appearance of pulmonary metastases, providing useful clues to properly address the diagnosis. Furthermore, we will deal with the promising applications of radiomics in this field. Finally, a focus on the hot-topic of pulmonary nodule management in patients with extra-thoracic neoplasms (ETNs) will be discussed.
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