Evidence map›Paper›PMID 40167904›Full record

ArticleNeuroinformatics2025

Genetic Insights into Brain Morphology: a Genome-Wide Association Study of Cortical Thickness and T

Nicholas J Kim, Nahian F Chowdhury, Kenneth H Buetow, Paul M Thompson, Andrei Irimia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas J KimUniversity of Southern California (Alfred E. Mann Department of Biomedical Engineering, Viterbi School of Engineering), Los Angeles, CA, USA.ORCID http://orcid.org/0009-0001-9647-2189
Nahian F ChowdhuryUniversity of Southern California (Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology), Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-3535-7280
Kenneth H BuetowArizona State University (School of Life Sciences Center for Social Dynamics and Complexity), Tempe, AZ, USA.ORCID http://orcid.org/0000-0003-4439-0939
Paul M ThompsonUniversity of Southern California (Mark and Mary Stevens Neuroimaging and Informatics Institute), Marina del Rey, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-4720-8867
Andrei IrimiaUniversity of Southern California (Alfred E. Mann Department of Biomedical Engineering, Viterbi School of Engineering), Los Angeles, CA, USA. irimia@usc.edu.ORCID http://orcid.org/0000-0002-9254-9388

Funding

USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE · 1999 to 2026
$17.9M
The role of sex in GABAergic-mediated, Alzheimer’s disease-related episodic memory impairments from mid to late lifeR01AG079512 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Teal S Eich · 2022 to 2026
$4.0M
Interpretable machine learning to synergize brain age estimation and neuroimaging geneticsR01AG079957 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Andrei Irimia · 2023 to 2026
$3.2M
Neurovascular calcification, Alzheimer’s disease and related dementias in two Native South American populationsRF1AG082201 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI IRIMIA, ANDREI · 2023 to 2023
$2.5M
Healthy Heart, Healthy Brain? A Pooled Life-course Cohort for Dementia Risk AssessmentRF1AG054443 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAFFE, KRISTINE, ZEKI AL HAZZOURI, ADINA · 2017 to 2017
$1.9M
Effects of blood-brain barrier disruption upon white matter connectivity subsequent to traumatic brain injuryR01NS100973 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI IRIMIA, ANDREI · 2017 to 2021
$1.6M
NIA NIH HHS P30 AG017265NIA NIH HHS R01 AG079512NIA NIH HHS R01 AG079957NIA NIH HHS RF1 AG054443NIA NIH HHS RF1 AG082201NIH HHS NS 100973, AG 082201, AG 054443, AG 079512, AG 079957NINDS NIH HHS R01 NS100973
6 · The paper itself

Abstract

In T

Indexed as

BrainBrain Cortical ThicknessCerebral CortexGenome-Wide Association StudyGray MatterMagnetic Resonance ImagingWhite MatterAdultAgedFemaleHumansMaleMiddle AgedPolymorphism, Single NucleotideBrain morphologyCortical thicknessDimensionality reductionGenome-wide association studyGray-white matter contrastT1-weighted MRIUMAP

Identifiers

PMID40167904
PMCPMC11961481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.