ArticleVeterinary research communications2025
Study of epidemiological and molecular characteristics of Brucella strains circulating in Kazakhstan.
Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Host and Pathogen Genetic Determinants of Brucellosis in Veterinary-One Health Interface: A Review.Veterinary sciences · 2026Review
- Brucellosis in Kazakhstan: Knowledge, Attitudes, and Practices Among Smallholder Farmers and Veterinary Specialists.Veterinary sciences · 2026Article
- Epidemiological landscape and genetic prospects for marker-assisted selection in Kazakh sheep.Frontiers in veterinary science · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Brucellosis is one of the most common zoonotic infectious diseases of animals. The causative agent of brucellosis is a highly conserved bacterium of the genus Brucella, which includes 14 species with minor genetic changes. Our work aimed to study the epidemiological and molecular characteristics of Brucella strains circulating in Kazakhstan, including the study of polymorphisms in critical virulence genes using single nucleotide polymorphism (SNP) analysis based on whole genome sequencing (WGS). A total of 21 Brucella isolates obtained in 2023-2024 from cattle, sheep and goats, horses, camels, pigs, dogs, and humans were analyzed. As a result of whole-genome sequencing, 69 virulence genes were detected. The genome of Brucella melitensis, the most virulent species of Brucella, was the most susceptible to changes. Among the 10 virulence genes studied using SNP, polymorphisms were found in 7 genes. Some genetic mutations resulted in amino acid changes in the coding sequences of these virulence genes. Knowledge of virulence factors and changes in their coding genes has practical implications for epidemiological studies in outbreak areas, their management, and the implementation of brucellosis control strategies.
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Registered trials
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