Evidence map›Paper›PMID 40167879›Full record

ArticleVeterinary research communications2025

Study of epidemiological and molecular characteristics of Brucella strains circulating in Kazakhstan.

Aida Daugaliyeva, Saule Daugaliyeva, Aspen Abutalip, Akmaral Adambayeva, Nazerke Kydyr, Simone Peletto

Abstract read
In one paragraph

Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aida DaugaliyevaKazakh Research Institute of Livestock and Fodder Production, Almaty, Kazakhstan.
Saule DaugaliyevaResearch and Production Center of Microbiology and Virology, Almaty, Kazakhstan. saule.daugalieva@mail.ru.
Aspen AbutalipKazakh Scientific Research Veterinary Institute, Almaty, Kazakhstan.
Akmaral AdambayevaKazakh Scientific Research Veterinary Institute, Almaty, Kazakhstan.
Nazerke KydyrKazakh National Agrarian Research University, Almaty, Kazakhstan.
Simone PelettoIstituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta, Turin, Italy.

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP19676357
6 · The paper itself

Abstract

Brucellosis is one of the most common zoonotic infectious diseases of animals. The causative agent of brucellosis is a highly conserved bacterium of the genus Brucella, which includes 14 species with minor genetic changes. Our work aimed to study the epidemiological and molecular characteristics of Brucella strains circulating in Kazakhstan, including the study of polymorphisms in critical virulence genes using single nucleotide polymorphism (SNP) analysis based on whole genome sequencing (WGS). A total of 21 Brucella isolates obtained in 2023-2024 from cattle, sheep and goats, horses, camels, pigs, dogs, and humans were analyzed. As a result of whole-genome sequencing, 69 virulence genes were detected. The genome of Brucella melitensis, the most virulent species of Brucella, was the most susceptible to changes. Among the 10 virulence genes studied using SNP, polymorphisms were found in 7 genes. Some genetic mutations resulted in amino acid changes in the coding sequences of these virulence genes. Knowledge of virulence factors and changes in their coding genes has practical implications for epidemiological studies in outbreak areas, their management, and the implementation of brucellosis control strategies.

Indexed as

BrucellaBrucellosisAnimalsCattleGoatsHumansKazakhstanPolymorphism, Single NucleotideSheepVirulenceVirulence FactorsWhole Genome SequencingVirulence FactorsBrucellosisSingle nucleotide polymorphismVirulence factorsVirulence genesWhole genome sequencing

Identifiers

PMID40167879
PMCPMC11961523

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.