Evidence map›Paper›PMID 40167827›Full record

ArticleEJNMMI research2025

Autoradiographic comparison between [

Antonio Aliaga, Joseph Therriault, Kely Quispialaya, Arturo Aliaga, Peter Kunach, Arthur C Macedo, Robert Hopewell, Nesrine Rahmouni, Jean-Paul Soucy, Gassan Massarweh and 15 more

Abstract read
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Longitudinal amyloid burden with combined [Imaging neuroscience (Cambridge, Mass.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Antonio Aliaga *Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0009-0006-9792-7815
Joseph Therriault *Translational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0002-7826-4781
Kely QuispialayaTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0009-0000-6982-7143
Arturo AliagaTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0001-6627-2939
Peter KunachTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0001-7428-6812
Arthur C MacedoTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0002-3957-0284
Robert HopewellMontreal Neurological Institute, Montreal, Canada.ORCID http://orcid.org/0000-0002-2478-5872
Nesrine RahmouniTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0009-0004-3081-8468
Jean-Paul SoucyMontreal Neurological Institute, Montreal, Canada.ORCID http://orcid.org/0000-0002-8422-2326
Gassan MassarwehMontreal Neurological Institute, Montreal, Canada.ORCID http://orcid.org/0000-0003-2259-9627
Marie-Christine GuiotDepartment of Neurology and Neurosurgery, McGill University, Montreal, Canada.
Tevy ChanTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0009-0001-9134-5949
Jesse KlostranecDepartment of Diagnostic Radiology, McGill University Health Center, Montreal, Canada.ORCID http://orcid.org/0000-0003-3553-0530
Aida Mary Abreu DiazDepartment of Pharmacology and Physiology, University of Montreal, Montreal, Canada.ORCID http://orcid.org/0000-0002-6301-3496
Andreia RochaDepartment of Psychiatry, Pittsburgh University, Pittsburgh, USA.ORCID http://orcid.org/0000-0003-1567-3374
Giovanna Carello-CollarGraduate Program in Biological Sciences: Biochemistry, Universidade Federal Do Rio Grande Do Sul, 2600 Ramiro Barcelos Street, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0003-4644-0151
Luiza S MachadoGraduate Program in Biological Sciences: Biochemistry, Universidade Federal Do Rio Grande Do Sul, 2600 Ramiro Barcelos Street, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0001-8387-3832
Marco Antônio De BastianiGraduate Program in Biological Sciences: Biochemistry, Universidade Federal Do Rio Grande Do Sul, 2600 Ramiro Barcelos Street, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0003-3924-5278
Débora Guerini de SouzaGraduate Program in Biological Sciences: Biochemistry, Universidade Federal Do Rio Grande Do Sul, 2600 Ramiro Barcelos Street, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0003-2982-4989
Diogo O SouzaGraduate Program in Biological Sciences: Biochemistry, Universidade Federal Do Rio Grande Do Sul, 2600 Ramiro Barcelos Street, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-4322-0404
Aline R ZimmerDepartment of Pharmacology, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-8309-7068
Serge GauthierTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada.ORCID http://orcid.org/0000-0003-4272-3330
Tharick A PascoalDepartment of Psychiatry, Pittsburgh University, Pittsburgh, USA.ORCID http://orcid.org/0000-0001-9057-8014
Eduardo R ZimmerTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada. eduardo.zimmer@ufrgs.br.ORCID http://orcid.org/0000-0002-5349-0053
Pedro Rosa-NetoTranslational Neuroimaging Laboratory, The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, 6875 La Salle Blvd - FBC Room 3149, Montreal, QC, H4H 1R3, Canada. pedro.rosa@mcgill.ca.ORCID http://orcid.org/0000-0001-9116-1376

Funding

Alzheimer's Association NIRG-12-92090Alzheimer's Association NIRP-12-259245CIHR 159815CIHR 162303CIHR MOP-11-51-31; RFN 152985Consortium canadien en neurodégénérescence associée au vieillissement MOP-11-51-31 -team 1Fondation Brain Canada 33397Fondation Brain Canada CFI Project 34874Fonds de Recherche du Québec - Santé 2020-VICO-279314Fonds de Recherche du Québec - Santé Chercheur Boursier
6 · The paper itself

Abstract

backgroundAmyloid-β imaging through positron emission tomography (PET) has significantly transformed Alzheimer's disease (AD) research. [

resultsFor both radiotracers, we found significant differences (p < 0.0001) between HC and AD tissues binding in the prefrontal cortex ([

conclusionsThis head-to-head study provides evidence that while [

Indexed as

[11C]PiB[18F]AZD4694 ([18F]NAV4694)Alzheimer’s diseaseAmyloid-PET tracerAutoradiography

Identifiers

PMID40167827
PMCPMC11961831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.