Evidence map›Paper›PMID 40167760›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Can the BIG score reliably predict outcomes in pediatric traumatic brain ınjury?

Abdulrahman Özel, Servet Yüce, Esma Şengenç, Esra Nur İlbeği, İzzettin Kaya, Şevval Özyılmaz Gazneli, Meltem Erol

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Abdulrahman ÖzelPediatric Intensive Care Unit, Department of Pediatrics, Bağcılar Training and Research Hospital, University of Health Sciences Türkiye, Merkez District, Dr. Sadık Ahmet Street. No:5, 34200, Istanbul, Türkiye. dr.abdulrahman.ozel@gmail.com.ORCID 0000-0001-8947-420X
Servet YüceDepartment of Public Health, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Türkiye.ORCID 0000-0002-5264-3038
Esma ŞengençDivision of Pediatric Neurology, Department of Pediatrics, Bağcılar Training and Research Hospital, University of Health Sciences Türkiye, Istanbul, Türkiye.ORCID 0000-0003-4002-785X
Esra Nur İlbeğiDepartment of Pediatrics, Bağcılar Training and Research Hospital, University of Health Sciences Türkiye, Istanbul, Türkiye.ORCID 0009-0003-9301-6027
İzzettin KayaDepartment of Pediatrics, Bağcılar Training and Research Hospital, University of Health Sciences Türkiye, Istanbul, Türkiye.ORCID 0009-0008-7263-9969
Şevval Özyılmaz GazneliDepartment of Pediatrics, Bağcılar Training and Research Hospital, University of Health Sciences Türkiye, Istanbul, Türkiye.ORCID 0009-0003-5701-5975
Meltem ErolDepartment of Pediatrics, Bağcılar Training and Research Hospital, University of Health Sciences Türkiye, Istanbul, Türkiye.ORCID 0000-0002-7672-1854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the prognostic value of the BIG score in predicting mortality and functional outcomes in pediatric patients with traumatic brain injury (TBI).

methodsA retrospective analysis was conducted on pediatric TBI patients admitted to the Pediatric Intensive Care Unit (PICU) between 2020 and 2024 at a tertiary hospital. Functional outcomes at discharge were assessed using the Functional Status Scale (FSS). Receiver operating characteristic (ROC) analysis determined the predictive accuracy of the BIG score, Pediatric Trauma Score (PTS), Pediatric Glasgow Coma Scale (pGCS), and Pediatric Risk of Mortality III (PRISM III).

resultsA total of 103 patients were included. The mortality rate was 13.6% (n = 14), and 21.4% of survivors had functional impairment at discharge. In non-survivors, the BIG score, PTS, pGCS, and PRISM III were significantly elevated (all p < 0.001). The AUC for predicting mortality was 0.966 (BIG score), 0.911 (PRISM III), 0.909 (pGCS), and 0.827 (PTS). For functional impairment, the AUC values were 0.815 (BIG score), 0.812 (pGCS), 0.715 (PRISM III), and 0.645 (PTS). Correlation analysis showed a strong association between FSS scores and mechanical ventilation duration (r = 0.786, p < 0.001) and PICU length of stay (r = 0.706, p < 0.001).

conclusionThe BIG score is a rapid, reliable predictor of mortality and functional outcomes in pediatric TBI patients, outperforming pGCS in patients with an initial pGCS of 3. Prospective studies are needed for further validation.

Indexed as

Brain Injuries, TraumaticAdolescentChildChild, PreschoolFemaleGlasgow Coma ScaleHumansInfantIntensive Care Units, PediatricMalePredictive Value of TestsPrognosisRetrospective StudiesChild mortalityEmergenciesFunctional statusMorbidityMultiple trauma

Identifiers

PMID40167760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.