ArticleNaunyn-Schmiedeberg's archives of pharmacology2025
Antitumor activity of functionalized iron oxide nanoparticles in Ehrlich tumor carcinoma-bearing mice enhanced by magnetic field.
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Therapeutic Metal Ions: Engineering Biomaterials for Multimodal Disease Treatment.International journal of nanomedicine · 2026Review
- Multiscale tumor characterization in histopathology via self-distilled transformers and topology-aware visual encoding.Scientific reports · 2025Article
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Authors and funding
3 authors.
Funding
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Abstract
Iron oxide nanoparticles show an intrinsic therapeutic effect on cancer growth. In vivo, the combination of iron oxide nanoparticles as magnetic particles and a low-frequency magnetic field significantly decreases the growth of Ehrlich tumor carcinoma in mice. Magnetic fields can vibrate and enhance iron oxide nanoparticles movement inside of cells, affecting their structure. In this study, iron oxide nanoparticles were synthesized and assessed by UV-visible spectrophotometer, dynamic light scattering (DLS), transmission electron microscope (TEM), X-ray diffraction (XRD), and vibrating sample magnetometer (VSM). The damage effects of iron oxide nanoparticles and low-frequency magnetic fields (0.5 T, 50 Hz) on tumor tissues were evaluated by assessment of DNA comet assay, and Fourier transformed infrared (FTIR), oxidative stress, assessment of inflammatory biomarkers, and histopathology studies. Also, the effect on the heart, liver, and kidney organs was studied. Our results suggest that iron oxide nanoparticles and magnetic fields could be applied to help in cancer treatment.
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Registered trials
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