Evidence map›Paper›PMID 40167621›Full record

Trial reportArchives of dermatological research2025

The efficacy of topical cetirizine using microneedling in androgenetic alopecia male patients.

Yasser Mostafa Gohary, Basma Mohamed Mohamed Elkastawy, Hasnaa Osama, Mona Elsayed Ahmed Abdellatif

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yasser Mostafa GoharyDermatology department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Basma Mohamed Mohamed ElkastawyDermatology department, New Cairo Specialized hospital, Cairo, Egypt.
Hasnaa OsamaDepartment of Clinical Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. hasnaa_osama2010@yahoo.com.ORCID http://orcid.org/0000-0003-2990-5981
Mona Elsayed Ahmed AbdellatifDermatology department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAndrogenetic alopecia (AGA) affects both sexes equally and lasts long. AGA is the most common kind of hair loss in men. Gradual, pattern-based hair thinning on the scalp is a hallmark of the disease. The front, back, center, and sides of a man's head are the most common areas where hair thinning and loss occur.

aimTo evaluate the efficacy of microneedling-administered topical cetirizine in treating androgenetic alopecia in men.

methodsA total of 80 AGA male patients were randomly assigned to this single-blind, parallel placebo-controlled study conducted at Beni-Suef University Hospital's Dermatology Outpatient Clinic. Researchers allocated 40 patients to undergo topical cetirizine microneedling (MN) and 40 patients to saline MN for 8 weeks.

resultsIn the 8th week, the cetirizine group demonstrated a greater prevalence of vellus hair (70.0%) than the saline group (30.0%), with a statistically significant difference (p-value = 0.001). The majority of patients administered cetirizine by MN exhibited enhanced hair density (80.0%) in contrast to 25.0% in the saline group, with a statistically significant difference between the two groups (p-value = 0.001). No notable adverse effects linked to the administration of cetirizine by MN were reported.

conclusionThe microneedling of 1% topical cetirizine proved efficient in promoting hair growth without problems in the treatment of male androgenetic alopecia.

Indexed as

AlopeciaCetirizineHairAdministration, CutaneousAdministration, TopicalAdultHumansMaleMiddle AgedNeedlesPercutaneous Collagen InductionSingle-Blind MethodTreatment OutcomeYoung AdultCetirizineAndrogenetic alopeciaCetirizineMaleMicroneedling

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.