SynthesisArchives of orthopaedic and trauma surgery2025
Comparison of surgical and non-surgical treatment for scoliosis in Duchenne muscular dystrophy: a systematic review and meta-analysis.
Synthesis in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDuchenne muscular dystrophy (DMD) is a neuromuscular disease caused by dystrophin gene mutations, which not only causes severe physical and psychological damage to the patient but also imposes a considerable economic burden on society. However, whether to aggressively surgical treatment for progressive scoliosis of DMD remains a conundrum. Therefore, we aimed to systematically evaluate the efficacy and prognosis of surgical treatment for DMD-associated scoliosis. MATERIALS AND
methodsPubMed, Embase, The Cochrane Library, China National Knowledge Infrastructure database, Wanfang database, China Science and Technology Journal Database, and China Biomedical Literature Database were searched for literature from the time of database creation until November 2022. The inclusion parameters were as follows: number of survivors, frequency of complications, preoperative, postoperative, and final follow-up Cobb's angles. Data were analyzed using RevMan 5.4.1 and Stata 12.0.
resultsSix studies were analyzed. Survival rates were higher [OR = 3.83, 95% CI (1.91, 7.66), p = 0.0001] and Cobb's angle improved [SMD, 1.79, 95% CI (150, 2.07), p < 0.00001] in the surgical group than in the non-surgical group. The non-surgical group had a lower complication rate than the surgical group did [OR = 8.75, 95% CI (1.02,75.08), p = 0.048].
conclusionsNotably, scoliosis-correction surgery improves patient survival. Besides, scoliosis-correction surgery provides patients with more stable Cobb angle. As expected, non-surgical treatment has the advantage of reducing the occurrence of complications.
Indexed as
Identifiers
40167615What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.