ArticleJournal of veterinary internal medicine
Equine Blood Microbiome in a Cohort of Clinically Healthy Trail Riding Horses.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Sex-specific gut mycobiome dysbiosis activates macrophage dectin-1 signaling to drive neurobehavioral deficits in EcoHIV-infected mice.Brain, behavior, and immunity · 2026Article
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundEmerging research suggests the presence of a blood microbiome in clinically healthy individuals. Characterizing bacterial composition and abundance in blood from a group of healthy horses is of clinical interest. HYPOTHESIS/
objectivesHorses in a closed herd environment will have blood microbiomes with similarities among individuals. ANIMALS: Twenty trail-riding horses of different breeds and ages living in relative isolation on a dry lot pasture in Colorado at 7680 ft elevation.
methodsCross-sectional study. Blood was collected from the jugular vein into serum, blood collection, and EDTA tubes. Samples were submitted to external laboratories for microbiome analysis and routine blood tests (CBC, serum biochemistry).
resultsVenous blood is not sterile in healthy horses. A total of 293 bacterial genera were identified in these samples, whereas most horses had 55 to 70 genera. The most dominant taxa were Gardnerella, Sporomusaceae, Kapabacteriales, Beijerinckiaceae, and Phascolarctobacterium. Principal coordinate analysis, investigating microbial structure diversity, identified large variability with no obvious clustering, indicating dissimilarity among bacterial populations in different horses. All blood samples contained genera with pathogenic potential for horses, such as Bacteroides spp., Clostridium spp., Peptostreptococcus spp., Streptococcus spp., and Staphylococcus spp. CONCLUSIONS AND CLINICAL IMPORTANCE: Clinically healthy horses had a diverse blood microbiome. Despite the relative isolation of the horses, their blood microbiota varied markedly among individuals. Investigating the bacteria in clinically healthy horse blood provides new insight into possible microbiome shifts that may result in clinical disease.
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