SynthesisThe British journal of psychiatry : the journal of mental science2026
Systematic review of the efficacy of pharmacological and non-pharmacological interventions for improving quality of life of people with dementia.
Synthesis in The British journal of psychiatry : the journal of mental science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07366346 (Telehealth-Adapted Compensatory Training and Intervention for Cognition for People With Mild Cognitive Impairment), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Telehealth-Adapted Compensatory Training and Intervention for Cognition for People With Mild Cognitive Impairment
Who cites it
12 citing papers in PubMed.
- Effects of a Comprehensive Intervention Program of Static-Dynamic Balance Training Combined with Reminiscence Therapy on the Level of Healthy Aging Among Older Adults in a Rural Community: A Randomized Controlled Trial.Clinical interventions in aging · 2025Trial
- Relationship Between Cognitive Performance and Anthropometric Status, Dietary Diversity, and Diet Quality in Older Turkish Adults: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Article
- [Early detection and active intervention in cognitive decline: A healthcare challenge].Anales del sistema sanitario de Navarra · 2026Article
- Mapping factors influencing the success of group activities for persons with dementia through the comprehensive process model of group engagement.The Gerontologist · 2026Article
- Gender Matters, Age Counts: Patterns of Antipsychotic Prescribing in Canadian Long-Term Care Homes.Healthcare management forum · 2026Article
- Metabolic dysfunction and insulin resistance across major dementias: A comprehensive narrative review of the TyG index as a predictive marker.Metabolism open · 2026Review
- Effects and Mechanisms of Probiotics, Prebiotics, Synbiotics, and Postbiotics for the Prevention and Management of Alzheimer's Disease: A Narrative Review.Antioxidants (Basel, Switzerland) · 2026Review
- Knowledge, awareness, and attitude of physical therapists on Alzheimer's disease in Syria.Scientific reports · 2026Article
- Nature-based interventions for people living with dementia and their carers: a scoping review.Frontiers in dementia · 2026Review
- The growing potential for multidisciplinary support and technology to enhance person-centred dementia care: a UK and US perspective.Frontiers in dementia · 2026Article
- Matters of the Heart: Co-Creating a Peer-Led Social Health Intervention for People Living with Dementia.Behavioral sciences (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeople with dementia (PwD) and their carers often consider maintaining good quality of life (QoL) more important than improvements in cognition or other symptoms of dementia. There is a clinical need for identifying interventions that can improve QoL of PwD. There are currently no evidence-based guidelines to help clinicians, patients and policy makers to make informed decisions regarding QoL in dementia.
aimsTo conduct the first comprehensive systematic review of all studies that investigated efficacy of any pharmacological or non-pharmacological intervention for improving QoL of PwD.
methodOur review team identified eligible studies by comprehensively searching nine databases. We completed quality assessment, extracted relevant data and performed GRADE assessment of eligible studies. We conducted meta-analyses when three or more studies investigated an intervention for improving QoL of PwD.
resultsWe screened 14 389 abstracts and included 324 eligible studies. Our meta-analysis confirmed level 1 evidence supporting the use of group cognitive stimulation therapy for improving QoL (standardised mean difference 0.25;
conclusionsCurrent evidence highlights the importance of non-pharmacological interventions and multidisciplinary care for supporting QoL of PwD. QoL should be prioritised when agreeing care plans. Further research focusing on QoL outcomes and investigating combined pharmacological and non-pharmacological interventions is urgently needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.